Kindler T - Search Results

1

Kindler T. Kindler T. Blood. 2018 Sep 13;132(11):1087-1088. doi: 10.1182/blood-2018-07-861716. Blood. 2018. PMID: 30213836 No abstract available.

2

Sustained complete hematologic remission after administration of the tyrosine kinase inhibitor imatinib mesylate in a patient with refractory, secondary AML.

Kindler T, Breitenbuecher F, Marx A, Hess G, Gschaidmeier H, Gamm H, Kirkpatrick CJ, Huber C, Fischer T. Kindler T, et al. Blood. 2003 Apr 15;101(8):2960-2. doi: 10.1182/blood-2002-05-1469. Epub 2002 Dec 12. Blood. 2003. PMID: 12480706

3

Efficacy and safety of imatinib in adult patients with c-kit-positive acute myeloid leukemia.

Kindler T, Breitenbuecher F, Marx A, Beck J, Hess G, Weinkauf B, Duyster J, Peschel C, Kirkpatrick CJ, Theobald M, Gschaidmeier H, Huber C, Fischer T. Kindler T, et al. Blood. 2004 May 15;103(10):3644-54. doi: 10.1182/blood-2003-06-2071. Epub 2004 Jan 15. Blood. 2004. PMID: 14726395 Clinical Trial.

4

Identification of a novel activating mutation (Y842C) within the activation loop of FLT3 in patients with acute myeloid leukemia (AML).

Kindler T, Breitenbuecher F, Kasper S, Estey E, Giles F, Feldman E, Ehninger G, Schiller G, Klimek V, Nimer SD, Gratwohl A, Choudhary CR, Mueller-Tidow C, Serve H, Gschaidmeier H, Cohen PS, Huber C, Fischer T. Kindler T, et al. Blood. 2005 Jan 1;105(1):335-40. doi: 10.1182/blood-2004-02-0660. Epub 2004 Sep 2. Blood. 2005. PMID: 15345593

5

Clinical resistance to the kinase inhibitor PKC412 in acute myeloid leukemia by mutation of Asn-676 in the FLT3 tyrosine kinase domain.

Heidel F, Solem FK, Breitenbuecher F, Lipka DB, Kasper S, Thiede MH, Brandts C, Serve H, Roesel J, Giles F, Feldman E, Ehninger G, Schiller GJ, Nimer S, Stone RM, Wang Y, Kindler T, Cohen PS, Huber C, Fischer T. Heidel F, et al. Among authors: kindler t. Blood. 2006 Jan 1;107(1):293-300. doi: 10.1182/blood-2005-06-2469. Epub 2005 Sep 8. Blood. 2006. PMID: 16150941

6

A novel molecular mechanism of primary resistance to FLT3-kinase inhibitors in AML.

Breitenbuecher F, Markova B, Kasper S, Carius B, Stauder T, Böhmer FD, Masson K, Rönnstrand L, Huber C, Kindler T, Fischer T. Breitenbuecher F, et al. Among authors: kindler t. Blood. 2009 Apr 23;113(17):4063-73. doi: 10.1182/blood-2007-11-126664. Epub 2009 Jan 14. Blood. 2009. PMID: 19144992

7

FLT3 as a therapeutic target in AML: still challenging after all these years.

Kindler T, Lipka DB, Fischer T. Kindler T, et al. Blood. 2010 Dec 9;116(24):5089-102. doi: 10.1182/blood-2010-04-261867. Epub 2010 Aug 12. Blood. 2010. PMID: 20705759 Review.

8

Targeting components of the alternative NHEJ pathway sensitizes KRAS mutant leukemic cells to chemotherapy.

Hähnel PS, Enders B, Sasca D, Roos WP, Kaina B, Bullinger L, Theobald M, Kindler T. Hähnel PS, et al. Among authors: kindler t. Blood. 2014 Apr 10;123(15):2355-66. doi: 10.1182/blood-2013-01-477620. Epub 2014 Feb 6. Blood. 2014. PMID: 24505083

9

Radiation sensitivity of human and murine peripheral blood lymphocytes, stem and progenitor cells.

Heylmann D, Rödel F, Kindler T, Kaina B. Heylmann D, et al. Among authors: kindler t. Biochim Biophys Acta. 2014 Aug;1846(1):121-9. doi: 10.1016/j.bbcan.2014.04.009. Epub 2014 May 4. Biochim Biophys Acta. 2014. PMID: 24797212 Review.

10

SIRT1 prevents genotoxic stress-induced p53 activation in acute myeloid leukemia.

Sasca D, Hähnel PS, Szybinski J, Khawaja K, Kriege O, Pante SV, Bullinger L, Strand S, Strand D, Theobald M, Kindler T. Sasca D, et al. Among authors: kindler t. Blood. 2014 Jul 3;124(1):121-33. doi: 10.1182/blood-2013-11-538819. Epub 2014 May 22. Blood. 2014. PMID: 24855208

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