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Apoptosis-derived membrane vesicles drive the cGAS-STING pathway and enhance type I IFN production in systemic lupus erythematosus.
Kato Y, Park J, Takamatsu H, Konaka H, Aoki W, Aburaya S, Ueda M, Nishide M, Koyama S, Hayama Y, Kinehara Y, Hirano T, Shima Y, Narazaki M, Kumanogoh A. Kato Y, et al. Among authors: kinehara y. Ann Rheum Dis. 2018 Oct;77(10):1507-1515. doi: 10.1136/annrheumdis-2018-212988. Epub 2018 Jun 26. Ann Rheum Dis. 2018. PMID: 29945921 Free PMC article.
Favorable response to trastuzumab plus irinotecan combination therapy in two patients with HER2-positive relapsed small-cell lung cancer.
Kinehara Y, Minami T, Kijima T, Hoshino S, Morimura O, Otsuka T, Hayama Y, Fukushima K, Takeuchi Y, Higashiguchi M, Miyake K, Hirata H, Nagatomo I, Inoue K, Takeda Y, Kida H, Kumanogoh A. Kinehara Y, et al. Lung Cancer. 2015 Mar;87(3):321-5. doi: 10.1016/j.lungcan.2015.01.003. Epub 2015 Jan 10. Lung Cancer. 2015. PMID: 25601188
LRRK1 is critical in the regulation of B-cell responses and CARMA1-dependent NF-κB activation.
Morimoto K, Baba Y, Shinohara H, Kang S, Nojima S, Kimura T, Ito D, Yoshida Y, Maeda Y, Sarashina-Kida H, Nishide M, Hosokawa T, Kato Y, Hayama Y, Kinehara Y, Okuno T, Takamatsu H, Hirano T, Shima Y, Narazaki M, Kurosaki T, Toyofuku T, Kumanogoh A. Morimoto K, et al. Among authors: kinehara y. Sci Rep. 2016 May 11;6:25738. doi: 10.1038/srep25738. Sci Rep. 2016. PMID: 27166870 Free PMC article.
Semaphorin 4D inhibits neutrophil activation and is involved in the pathogenesis of neutrophil-mediated autoimmune vasculitis.
Nishide M, Nojima S, Ito D, Takamatsu H, Koyama S, Kang S, Kimura T, Morimoto K, Hosokawa T, Hayama Y, Kinehara Y, Kato Y, Nakatani T, Nakanishi Y, Tsuda T, Park JH, Hirano T, Shima Y, Narazaki M, Morii E, Kumanogoh A. Nishide M, et al. Among authors: kinehara y. Ann Rheum Dis. 2017 Aug;76(8):1440-1448. doi: 10.1136/annrheumdis-2016-210706. Epub 2017 Apr 17. Ann Rheum Dis. 2017. PMID: 28416516 Free PMC article.
Trastuzumab emtansine suppresses the growth of HER2-positive small-cell lung cancer in preclinical models.
Morimura O, Minami T, Kijima T, Koyama S, Otsuka T, Kinehara Y, Osa A, Higashiguchi M, Miyake K, Nagatomo I, Hirata H, Iwahori K, Takimoto T, Takeda Y, Kida H, Kumanogoh A. Morimura O, et al. Among authors: kinehara y. Biochem Biophys Res Commun. 2017 Jul 8;488(4):596-602. doi: 10.1016/j.bbrc.2017.05.090. Epub 2017 May 17. Biochem Biophys Res Commun. 2017. PMID: 28526406
Lamtor1 Is Critically Required for CD4+ T Cell Proliferation and Regulatory T Cell Suppressive Function.
Hosokawa T, Kimura T, Nada S, Okuno T, Ito D, Kang S, Nojima S, Yamashita K, Nakatani T, Hayama Y, Kato Y, Kinehara Y, Nishide M, Mikami N, Koyama S, Takamatsu H, Okuzaki D, Ohkura N, Sakaguchi S, Okada M, Kumanogoh A. Hosokawa T, et al. Among authors: kinehara y. J Immunol. 2017 Sep 15;199(6):2008-2019. doi: 10.4049/jimmunol.1700157. Epub 2017 Aug 2. J Immunol. 2017. PMID: 28768723
Lysosomal Protein Lamtor1 Controls Innate Immune Responses via Nuclear Translocation of Transcription Factor EB.
Hayama Y, Kimura T, Takeda Y, Nada S, Koyama S, Takamatsu H, Kang S, Ito D, Maeda Y, Nishide M, Nojima S, Sarashina-Kida H, Hosokawa T, Kinehara Y, Kato Y, Nakatani T, Nakanishi Y, Tsuda T, Koba T, Okada M, Kumanogoh A. Hayama Y, et al. Among authors: kinehara y. J Immunol. 2018 Jun 1;200(11):3790-3800. doi: 10.4049/jimmunol.1701283. Epub 2018 Apr 23. J Immunol. 2018. PMID: 29686050
26 results