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Year Number of Results
2007 2
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2011 1
2012 3
2013 1
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2017 3
2018 3
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2022 1
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57 results

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Page 1
Halting coronavirus polymerase.
Kirchdoerfer RN. Kirchdoerfer RN. J Biol Chem. 2020 Apr 10;295(15):4780-4781. doi: 10.1074/jbc.H120.013397. J Biol Chem. 2020. PMID: 32277065 Free PMC article.
Spike and nsp6 are key determinants of SARS-CoV-2 Omicron BA.1 attenuation.
Chen DY, Chin CV, Kenney D, Tavares AH, Khan N, Conway HL, Liu G, Choudhary MC, Gertje HP, O'Connell AK, Adams S, Kotton DN, Herrmann A, Ensser A, Connor JH, Bosmann M, Li JZ, Gack MU, Baker SC, Kirchdoerfer RN, Kataria Y, Crossland NA, Douam F, Saeed M. Chen DY, et al. Among authors: kirchdoerfer rn. Nature. 2023 Mar;615(7950):143-150. doi: 10.1038/s41586-023-05697-2. Epub 2023 Jan 11. Nature. 2023. PMID: 36630998
SARS-CoV-2 nsp15 enhances viral virulence by subverting host antiviral defenses.
Caobi A, Su CM, Beusch CM, Kenney D, Darling TL, Feng S, Semaan M, Wacquiez A, Sanders NL, Tully ES, Chen DY, Evdokimova M, Ding Z, Jones D, Alysandratos KD, Mizgerd JP, Kirchdoerfer RN, Kotton DN, Douam F, Crossland NA, Boon ACM, Gordon DE, Baker SC, Saeed M. Caobi A, et al. Among authors: kirchdoerfer rn. Proc Natl Acad Sci U S A. 2025 Jun 17;122(24):e2426528122. doi: 10.1073/pnas.2426528122. Epub 2025 Jun 12. Proc Natl Acad Sci U S A. 2025. PMID: 40504150 Free PMC article.
Coronavirus endoribonuclease antagonizes ZBP1-mediated necroptosis and delays multiple cell death pathways.
Evdokimova M, Feng S, Caobi A, Moreira FR, Jones D, Alysandratos KD, Tully ES, Kotton DN, Boyd DF, Banach BS, Kirchdoerfer RN, Saeed M, Baker SC. Evdokimova M, et al. Among authors: kirchdoerfer rn. Proc Natl Acad Sci U S A. 2025 Mar 11;122(10):e2419620122. doi: 10.1073/pnas.2419620122. Epub 2025 Mar 4. Proc Natl Acad Sci U S A. 2025. PMID: 40035769 Free PMC article.
A post-assembly conformational change makes the SARS-CoV-2 polymerase elongation-competent.
Klein M, Das A, Bera SC, Anderson TK, Kocincova D, Lee HW, Wang B, Papini FS, Marecki JC, Arnold JJ, Cameron CE, Raney KD, Artsimovitch I, Götte M, Kirchdoerfer RN, Depken M, Dulin D. Klein M, et al. Among authors: kirchdoerfer rn. Nucleic Acids Res. 2025 May 22;53(10):gkaf450. doi: 10.1093/nar/gkaf450. Nucleic Acids Res. 2025. PMID: 40464687 Free PMC article.
CD81 is a receptor for equine arteritis virus (family: Arteriviridae).
Maloney SM, Shaw TM, Nennig KM, Larsen MS, Shah A, Kumar A, Marcotrigiano J, Grove J, Snijder EJ, Kirchdoerfer RN, Bailey AL. Maloney SM, et al. Among authors: kirchdoerfer rn. mBio. 2025 Jul 9;16(7):e0062325. doi: 10.1128/mbio.00623-25. Epub 2025 May 27. mBio. 2025. PMID: 40422661 Free PMC article.
Interfering with nucleotide excision by the coronavirus 3'-to-5' exoribonuclease.
Chinthapatla R, Sotoudegan M, Srivastava P, Anderson TK, Moustafa IM, Passow KT, Kennelly SA, Moorthy R, Dulin D, Feng JY, Harki DA, Kirchdoerfer RN, Cameron CE, Arnold JJ. Chinthapatla R, et al. Among authors: kirchdoerfer rn. Nucleic Acids Res. 2023 Jan 11;51(1):315-336. doi: 10.1093/nar/gkac1177. Nucleic Acids Res. 2023. PMID: 36546762 Free PMC article.
57 results