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The C-terminal regulatory domain is the RNA 5'-triphosphate sensor of RIG-I.
Cui S, Eisenächer K, Kirchhofer A, Brzózka K, Lammens A, Lammens K, Fujita T, Conzelmann KK, Krug A, Hopfner KP. Cui S, et al. Among authors: kirchhofer a. Mol Cell. 2008 Feb 1;29(2):169-79. doi: 10.1016/j.molcel.2007.10.032. Mol Cell. 2008. PMID: 18243112 Free article.
The regulatory domain of the RIG-I family ATPase LGP2 senses double-stranded RNA.
Pippig DA, Hellmuth JC, Cui S, Kirchhofer A, Lammens K, Lammens A, Schmidt A, Rothenfusser S, Hopfner KP. Pippig DA, et al. Among authors: kirchhofer a. Nucleic Acids Res. 2009 Apr;37(6):2014-25. doi: 10.1093/nar/gkp059. Epub 2009 Feb 10. Nucleic Acids Res. 2009. PMID: 19208642 Free PMC article.
Modulation of protein properties in living cells using nanobodies.
Kirchhofer A, Helma J, Schmidthals K, Frauer C, Cui S, Karcher A, Pellis M, Muyldermans S, Casas-Delucchi CS, Cardoso MC, Leonhardt H, Hopfner KP, Rothbauer U. Kirchhofer A, et al. Nat Struct Mol Biol. 2010 Jan;17(1):133-8. doi: 10.1038/nsmb.1727. Epub 2009 Dec 13. Nat Struct Mol Biol. 2010. PMID: 20010839
Plasma metabolomics reveal alterations of sphingo- and glycerophospholipid levels in non-diabetic carriers of the transcription factor 7-like 2 polymorphism rs7903146.
Then C, Wahl S, Kirchhofer A, Grallert H, Krug S, Kastenmüller G, Römisch-Margl W, Claussnitzer M, Illig T, Heier M, Meisinger C, Adamski J, Thorand B, Huth C, Peters A, Prehn C, Heukamp I, Laumen H, Lechner A, Hauner H, Seissler J. Then C, et al. Among authors: kirchhofer a. PLoS One. 2013 Oct 24;8(10):e78430. doi: 10.1371/journal.pone.0078430. eCollection 2013. PLoS One. 2013. PMID: 24205231 Free PMC article.