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The mitochondrial calcium uniporter is a highly selective ion channel.
Kirichok Y, Krapivinsky G, Clapham DE. Kirichok Y, et al. Nature. 2004 Jan 22;427(6972):360-4. doi: 10.1038/nature02246. Nature. 2004. PMID: 14737170
Patch-Clamp Analysis of the Mitochondrial Calcium Uniporter.
Garg V, Kirichok YY. Garg V, et al. Among authors: kirichok yy. Methods Mol Biol. 2019;1925:75-86. doi: 10.1007/978-1-4939-9018-4_7. Methods Mol Biol. 2019. PMID: 30674018
Mitochondrial Ca2+ uniporter and CaMKII in heart.
Fieni F, Johnson DE, Hudmon A, Kirichok Y. Fieni F, et al. Nature. 2014 Sep 25;513(7519):E1-2. doi: 10.1038/nature13626. Nature. 2014. PMID: 25254480 Free PMC article.
Keeping a lid on calcium uptake.
Garg V, Kirichok Y. Garg V, et al. Among authors: kirichok y. Elife. 2016 Jun 3;5:e17293. doi: 10.7554/eLife.17293. Elife. 2016. PMID: 27258801 Free PMC article.
H+ transport is an integral function of the mitochondrial ADP/ATP carrier.
Bertholet AM, Chouchani ET, Kazak L, Angelin A, Fedorenko A, Long JZ, Vidoni S, Garrity R, Cho J, Terada N, Wallace DC, Spiegelman BM, Kirichok Y. Bertholet AM, et al. Among authors: kirichok y. Nature. 2019 Jul;571(7766):515-520. doi: 10.1038/s41586-019-1400-3. Epub 2019 Jul 24. Nature. 2019. PMID: 31341297 Free PMC article.
Activity of the mitochondrial calcium uniporter varies greatly between tissues.
Fieni F, Lee SB, Jan YN, Kirichok Y. Fieni F, et al. Nat Commun. 2012;3:1317. doi: 10.1038/ncomms2325. Nat Commun. 2012. PMID: 23271651 Free PMC article.
Ion channels that control fertility in mammalian spermatozoa.
Navarro B, Kirichok Y, Chung JJ, Clapham DE. Navarro B, et al. Int J Dev Biol. 2008;52(5-6):607-13. doi: 10.1387/ijdb.072554bn. Int J Dev Biol. 2008. PMID: 18649274 Free PMC article. Review.
KSper, a pH-sensitive K+ current that controls sperm membrane potential.
Navarro B, Kirichok Y, Clapham DE. Navarro B, et al. Proc Natl Acad Sci U S A. 2007 May 1;104(18):7688-92. doi: 10.1073/pnas.0702018104. Epub 2007 Apr 25. Proc Natl Acad Sci U S A. 2007. PMID: 17460039 Free PMC article.
All four CatSper ion channel proteins are required for male fertility and sperm cell hyperactivated motility.
Qi H, Moran MM, Navarro B, Chong JA, Krapivinsky G, Krapivinsky L, Kirichok Y, Ramsey IS, Quill TA, Clapham DE. Qi H, et al. Proc Natl Acad Sci U S A. 2007 Jan 23;104(4):1219-23. doi: 10.1073/pnas.0610286104. Epub 2007 Jan 16. Proc Natl Acad Sci U S A. 2007. PMID: 17227845 Free PMC article.
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