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Ticagrelor inhibits adenosine uptake in vitro and enhances adenosine-mediated hyperemia responses in a canine model.
van Giezen JJ, Sidaway J, Glaves P, Kirk I, Björkman JA. van Giezen JJ, et al. Among authors: kirk i. J Cardiovasc Pharmacol Ther. 2012 Jun;17(2):164-72. doi: 10.1177/1074248411410883. Epub 2011 Jun 22. J Cardiovasc Pharmacol Ther. 2012. PMID: 21697355
From ATP to AZD6140: the discovery of an orally active reversible P2Y12 receptor antagonist for the prevention of thrombosis.
Springthorpe B, Bailey A, Barton P, Birkinshaw TN, Bonnert RV, Brown RC, Chapman D, Dixon J, Guile SD, Humphries RG, Hunt SF, Ince F, Ingall AH, Kirk IP, Leeson PD, Leff P, Lewis RJ, Martin BP, McGinnity DF, Mortimore MP, Paine SW, Pairaudeau G, Patel A, Rigby AJ, Riley RJ, Teobald BJ, Tomlinson W, Webborn PJ, Willis PA. Springthorpe B, et al. Among authors: kirk ip. Bioorg Med Chem Lett. 2007 Nov 1;17(21):6013-8. doi: 10.1016/j.bmcl.2007.07.057. Epub 2007 Aug 19. Bioorg Med Chem Lett. 2007. PMID: 17827008
Inhibition by KF17837 of adenosine A2A receptor-mediated modulation of striatal GABA and ACh release.
Kurokawa M, Kirk IP, Kirkpatrick KA, Kase H, Richardson PJ. Kurokawa M, et al. Among authors: kirk ip. Br J Pharmacol. 1994 Sep;113(1):43-8. doi: 10.1111/j.1476-5381.1994.tb16171.x. Br J Pharmacol. 1994. PMID: 7812630 Free PMC article.
P2Y1-receptors in human platelets which are pharmacologically distinct from P2Y(ADP)-receptors.
Fagura MS, Dainty IA, McKay GD, Kirk IP, Humphries RG, Robertson MJ, Dougall IG, Leff P. Fagura MS, et al. Among authors: kirk ip. Br J Pharmacol. 1998 May;124(1):157-64. doi: 10.1038/sj.bjp.0701827. Br J Pharmacol. 1998. PMID: 9630355 Free PMC article.
In platelets, AR-C66096 at a concentration (0.1 microM) approximately 100 fold greater than its known P2Y(ADP) receptor affinity, had no effect on ADP-induced increases in [Ca2+]i. 4. ...In summary, the results of this study indicate that human washed platelets contain P2Y …
In platelets, AR-C66096 at a concentration (0.1 microM) approximately 100 fold greater than its known P2Y(ADP) receptor affinity, had no eff …
Adenosine A2a receptor-mediated modulation of striatal [3H]GABA and [3H]acetylcholine release.
Kirk IP, Richardson PJ. Kirk IP, et al. J Neurochem. 1994 Mar;62(3):960-6. doi: 10.1046/j.1471-4159.1994.62030960.x. J Neurochem. 1994. PMID: 8113816
Further characterization of [3H]-CGS 21680 binding sites in the rat striatum and cortex.
Kirk IP, Richardson PJ. Kirk IP, et al. Br J Pharmacol. 1995 Jan;114(2):537-43. doi: 10.1111/j.1476-5381.1995.tb13260.x. Br J Pharmacol. 1995. PMID: 7881753 Free PMC article.
Inhibition of striatal GABA release by the adenosine A2a receptor is not mediated by increases in cyclic AMP.
Kirk IP, Richardson PJ. Kirk IP, et al. J Neurochem. 1995 Jun;64(6):2801-9. doi: 10.1046/j.1471-4159.1995.64062801.x. J Neurochem. 1995. PMID: 7760061
The C6-2B glioma cell P2Y(AC) receptor is pharmacologically and molecularly identical to the platelet P2Y(12) receptor.
Jin J, Tomlinson W, Kirk IP, Kim YB, Humphries RG, Kunapuli SP. Jin J, et al. Among authors: kirk ip. Br J Pharmacol. 2001 Jun;133(4):521-8. doi: 10.1038/sj.bjp.0704114. Br J Pharmacol. 2001. PMID: 11399669 Free PMC article.
The role of Hebbian learning in human perception: a methodological and theoretical review of the human Visual Long-Term Potentiation paradigm.
Sumner RL, Spriggs MJ, Muthukumaraswamy SD, Kirk IJ. Sumner RL, et al. Among authors: kirk ij. Neurosci Biobehav Rev. 2020 Aug;115:220-237. doi: 10.1016/j.neubiorev.2020.03.013. Epub 2020 Jun 18. Neurosci Biobehav Rev. 2020. PMID: 32562886 Review.
Erratum to "Methamphetamine use and cognitive function: A systematic review of neuroimaging research" [Drug Alcohol Depend. 194 (2019) 75-87].
Sabrini S, Wang GY, Lin JC, Kirk IJ, Curley LE. Sabrini S, et al. Among authors: kirk ij. Drug Alcohol Depend. 2020 Feb 1;207:107812. doi: 10.1016/j.drugalcdep.2019.107812. Epub 2020 Jan 8. Drug Alcohol Depend. 2020. PMID: 31927160 No abstract available.
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