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Alzheimer's therapeutics targeting amyloid beta 1-42 oligomers II: Sigma-2/PGRMC1 receptors mediate Abeta 42 oligomer binding and synaptotoxicity.
Izzo NJ, Xu J, Zeng C, Kirk MJ, Mozzoni K, Silky C, Rehak C, Yurko R, Look G, Rishton G, Safferstein H, Cruchaga C, Goate A, Cahill MA, Arancio O, Mach RH, Craven R, Head E, LeVine H 3rd, Spires-Jones TL, Catalano SM. Izzo NJ, et al. Among authors: kirk mj. PLoS One. 2014 Nov 12;9(11):e111899. doi: 10.1371/journal.pone.0111899. eCollection 2014. PLoS One. 2014. PMID: 25390692 Free PMC article.
Experimental evidence for the age dependence of tau protein spread in the brain.
Wegmann S, Bennett RE, Delorme L, Robbins AB, Hu M, McKenzie D, Kirk MJ, Schiantarelli J, Tunio N, Amaral AC, Fan Z, Nicholls S, Hudry E, Hyman BT. Wegmann S, et al. Among authors: kirk mj. Sci Adv. 2019 Jun 26;5(6):eaaw6404. doi: 10.1126/sciadv.aaw6404. eCollection 2019 Jun. Sci Adv. 2019. PMID: 31249873 Free PMC article.
Removing endogenous tau does not prevent tau propagation yet reduces its neurotoxicity.
Wegmann S, Maury EA, Kirk MJ, Saqran L, Roe A, DeVos SL, Nicholls S, Fan Z, Takeda S, Cagsal-Getkin O, William CM, Spires-Jones TL, Pitstick R, Carlson GA, Pooler AM, Hyman BT. Wegmann S, et al. Among authors: kirk mj. EMBO J. 2015 Dec 14;34(24):3028-41. doi: 10.15252/embj.201592748. Epub 2015 Nov 4. EMBO J. 2015. PMID: 26538322 Free PMC article.
In vitro activity of daclatasvir on hepatitis C virus genotype 3 NS5A.
Wang C, Valera L, Jia L, Kirk MJ, Gao M, Fridell RA. Wang C, et al. Among authors: kirk mj. Antimicrob Agents Chemother. 2013 Jan;57(1):611-3. doi: 10.1128/AAC.01874-12. Epub 2012 Oct 22. Antimicrob Agents Chemother. 2013. PMID: 23089758 Free PMC article.
15 results