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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 1
1972 3
1973 4
1974 1
1977 4
1978 3
1979 2
1981 5
1982 3
1983 8
1984 6
1985 2
1986 3
1987 7
1988 6
1989 5
1990 3
1992 5
1993 6
1994 3
1995 2
1996 4
1997 3
1998 5
1999 3
2000 2
2001 4
2002 5
2003 1
2004 1
2005 1
2006 6
2007 6
2008 2
2009 2
2010 11
2011 6
2012 6
2013 6
2014 14
2015 15
2016 19
2017 17
2018 13
2019 22
2020 23
2021 36
2022 26
2023 11

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323 results

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Page 1
Senolytic drugs: from discovery to translation.
Kirkland JL, Tchkonia T. Kirkland JL, et al. J Intern Med. 2020 Nov;288(5):518-536. doi: 10.1111/joim.13141. Epub 2020 Aug 4. J Intern Med. 2020. PMID: 32686219 Free PMC article. Review.
Sarcopenia: Aging-Related Loss of Muscle Mass and Function.
Larsson L, Degens H, Li M, Salviati L, Lee YI, Thompson W, Kirkland JL, Sandri M. Larsson L, et al. Among authors: kirkland jl. Physiol Rev. 2019 Jan 1;99(1):427-511. doi: 10.1152/physrev.00061.2017. Physiol Rev. 2019. PMID: 30427277 Free PMC article. Review.
Cellular senescence: the good, the bad and the unknown.
Huang W, Hickson LJ, Eirin A, Kirkland JL, Lerman LO. Huang W, et al. Among authors: kirkland jl. Nat Rev Nephrol. 2022 Oct;18(10):611-627. doi: 10.1038/s41581-022-00601-z. Epub 2022 Aug 3. Nat Rev Nephrol. 2022. PMID: 35922662 Free PMC article. Review.
Cellular Senescence: A Translational Perspective.
Kirkland JL, Tchkonia T. Kirkland JL, et al. EBioMedicine. 2017 Jul;21:21-28. doi: 10.1016/j.ebiom.2017.04.013. Epub 2017 Apr 12. EBioMedicine. 2017. PMID: 28416161 Free PMC article. Review.
Cellular senescence and senolytics: the path to the clinic.
Chaib S, Tchkonia T, Kirkland JL. Chaib S, et al. Among authors: kirkland jl. Nat Med. 2022 Aug;28(8):1556-1568. doi: 10.1038/s41591-022-01923-y. Epub 2022 Aug 11. Nat Med. 2022. PMID: 35953721 Free PMC article. Review.
Senolytics improve physical function and increase lifespan in old age.
Xu M, Pirtskhalava T, Farr JN, Weigand BM, Palmer AK, Weivoda MM, Inman CL, Ogrodnik MB, Hachfeld CM, Fraser DG, Onken JL, Johnson KO, Verzosa GC, Langhi LGP, Weigl M, Giorgadze N, LeBrasseur NK, Miller JD, Jurk D, Singh RJ, Allison DB, Ejima K, Hubbard GB, Ikeno Y, Cubro H, Garovic VD, Hou X, Weroha SJ, Robbins PD, Niedernhofer LJ, Khosla S, Tchkonia T, Kirkland JL. Xu M, et al. Among authors: kirkland jl. Nat Med. 2018 Aug;24(8):1246-1256. doi: 10.1038/s41591-018-0092-9. Epub 2018 Jul 9. Nat Med. 2018. PMID: 29988130 Free PMC article.
A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues.
Saul D, Kosinsky RL, Atkinson EJ, Doolittle ML, Zhang X, LeBrasseur NK, Pignolo RJ, Robbins PD, Niedernhofer LJ, Ikeno Y, Jurk D, Passos JF, Hickson LJ, Xue A, Monroe DG, Tchkonia T, Kirkland JL, Farr JN, Khosla S. Saul D, et al. Among authors: kirkland jl. Nat Commun. 2022 Aug 16;13(1):4827. doi: 10.1038/s41467-022-32552-1. Nat Commun. 2022. PMID: 35974106 Free PMC article.
Fisetin is a senotherapeutic that extends health and lifespan.
Yousefzadeh MJ, Zhu Y, McGowan SJ, Angelini L, Fuhrmann-Stroissnigg H, Xu M, Ling YY, Melos KI, Pirtskhalava T, Inman CL, McGuckian C, Wade EA, Kato JI, Grassi D, Wentworth M, Burd CE, Arriaga EA, Ladiges WL, Tchkonia T, Kirkland JL, Robbins PD, Niedernhofer LJ. Yousefzadeh MJ, et al. Among authors: kirkland jl. EBioMedicine. 2018 Oct;36:18-28. doi: 10.1016/j.ebiom.2018.09.015. Epub 2018 Sep 29. EBioMedicine. 2018. PMID: 30279143 Free PMC article.
Cellular senescence mediates fibrotic pulmonary disease.
Schafer MJ, White TA, Iijima K, Haak AJ, Ligresti G, Atkinson EJ, Oberg AL, Birch J, Salmonowicz H, Zhu Y, Mazula DL, Brooks RW, Fuhrmann-Stroissnigg H, Pirtskhalava T, Prakash YS, Tchkonia T, Robbins PD, Aubry MC, Passos JF, Kirkland JL, Tschumperlin DJ, Kita H, LeBrasseur NK. Schafer MJ, et al. Among authors: kirkland jl. Nat Commun. 2017 Feb 23;8:14532. doi: 10.1038/ncomms14532. Nat Commun. 2017. PMID: 28230051 Free PMC article.
323 results