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Hepatic arterial infusion of a replication-selective oncolytic adenovirus (dl1520): phase II viral, immunologic, and clinical endpoints.
Reid T, Galanis E, Abbruzzese J, Sze D, Wein LM, Andrews J, Randlev B, Heise C, Uprichard M, Hatfield M, Rome L, Rubin J, Kirn D. Reid T, et al. Cancer Res. 2002 Nov 1;62(21):6070-9. Cancer Res. 2002. PMID: 12414631 Clinical Trial.
Intravascular adenoviral agents in cancer patients: lessons from clinical trials.
Reid T, Warren R, Kirn D. Reid T, et al. Cancer Gene Ther. 2002 Dec;9(12):979-86. doi: 10.1038/sj.cgt.7700539. Cancer Gene Ther. 2002. PMID: 12522437 Free PMC article. Review.
E3 gene manipulations affect oncolytic adenovirus activity in immunocompetent tumor models.
Wang Y, Hallden G, Hill R, Anand A, Liu TC, Francis J, Brooks G, Lemoine N, Kirn D. Wang Y, et al. Nat Biotechnol. 2003 Nov;21(11):1328-35. doi: 10.1038/nbt887. Epub 2003 Oct 12. Nat Biotechnol. 2003. PMID: 14555956
Oncolytic biotherapy: a novel therapeutic plafform.
Hawkins LK, Lemoine NR, Kirn D. Hawkins LK, et al. Lancet Oncol. 2002 Jan;3(1):17-26. doi: 10.1016/s1470-2045(01)00618-0. Lancet Oncol. 2002. PMID: 11905600 Review.
The emerging fields of suicide gene therapy and virotherapy.
Kirn D, Niculescu-Duvaz I, Hallden G, Springer CJ. Kirn D, et al. Trends Mol Med. 2002;8(4 Suppl):S68-73. doi: 10.1016/s1471-4914(02)02318-3. Trends Mol Med. 2002. PMID: 11927291 Review.
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