Kirschbaum BJ - Search Results

1

Leflunomide: an immunomodulatory drug for the treatment of rheumatoid arthritis and other autoimmune diseases.

Herrmann ML, Schleyerbach R, Kirschbaum BJ. Herrmann ML, et al. Among authors: kirschbaum bj. Immunopharmacology. 2000 May;47(2-3):273-89. doi: 10.1016/s0162-3109(00)00191-0. Immunopharmacology. 2000. PMID: 10878294 Review.

2

Leflunomide inhibits pyrimidine de novo synthesis in mitogen-stimulated T-lymphocytes from healthy humans.

Rückemann K, Fairbanks LD, Carrey EA, Hawrylowicz CM, Richards DF, Kirschbaum B, Simmonds HA. Rückemann K, et al. J Biol Chem. 1998 Aug 21;273(34):21682-91. doi: 10.1074/jbc.273.34.21682. J Biol Chem. 1998. PMID: 9705303

3

Mechanism of action for leflunomide in rheumatoid arthritis.

Fox RI, Herrmann ML, Frangou CG, Wahl GM, Morris RE, Strand V, Kirschbaum BJ. Fox RI, et al. Among authors: kirschbaum bj. Clin Immunol. 1999 Dec;93(3):198-208. doi: 10.1006/clim.1999.4777. Clin Immunol. 1999. PMID: 10600330 Review.

4

How does leflunomide modulate the immune response in rheumatoid arthritis?

Fox RI, Herrmann ML, Frangou CG, Wahl GM, Morris RE, Kirschbaum BJ. Fox RI, et al. Among authors: kirschbaum bj. BioDrugs. 1999 Oct;12(4):301-15. doi: 10.2165/00063030-199912040-00007. BioDrugs. 1999. PMID: 18031184

5

Osteoarthritis - an untreatable disease?

Wieland HA, Michaelis M, Kirschbaum BJ, Rudolphi KA. Wieland HA, et al. Among authors: kirschbaum bj. Nat Rev Drug Discov. 2005 Apr;4(4):331-44. doi: 10.1038/nrd1693. Nat Rev Drug Discov. 2005. PMID: 15803196 Review.

6

Identification and characterization of potential new therapeutic targets in inflammatory and autoimmune diseases.

Mangold U, Dax CI, Saar K, Schwab W, Kirschbaum B, Müllner S. Mangold U, et al. Eur J Biochem. 1999 Dec;266(3):1184-91. doi: 10.1046/j.1432-1327.1999.00978.x. Eur J Biochem. 1999. PMID: 10583416

7

The mammalian homologue of Prp16p is overexpressed in a cell line tolerant to Leflunomide, a new immunoregulatory drug effective against rheumatoid arthritis.

Ortlepp D, Laggerbauer B, Müllner S, Achsel T, Kirschbaum B, Lührmann R. Ortlepp D, et al. RNA. 1998 Aug;4(8):1007-18. doi: 10.1017/s1355838298980554. RNA. 1998. PMID: 9701291 Free PMC article.

8

Functional expression of a fragment of human dihydroorotate dehydrogenase by means of the baculovirus expression vector system, and kinetic investigation of the purified recombinant enzyme.

Knecht W, Bergjohann U, Gonski S, Kirschbaum B, Löffler M. Knecht W, et al. Eur J Biochem. 1996 Aug 15;240(1):292-301. doi: 10.1111/j.1432-1033.1996.0292h.x. Eur J Biochem. 1996. PMID: 8925840

9

Methotrexate inhibits the first committed step of purine biosynthesis in mitogen-stimulated human T-lymphocytes: a metabolic basis for efficacy in rheumatoid arthritis?

Fairbanks LD, Rückemann K, Qiu Y, Hawrylowicz CM, Richards DF, Swaminathan R, Kirschbaum B, Simmonds HA. Fairbanks LD, et al. Biochem J. 1999 Aug 15;342 ( Pt 1)(Pt 1):143-52. Biochem J. 1999. PMID: 10432311 Free PMC article.

10

Simultaneous separation by high-performance liquid chromatography of carbamoyl aspartate, carbamoyl phosphate and dihydroorotic acid.

Fairbanks LD, Carrey EA, Rückemann K, Swaminathan R, Kirschbaum B, Simmonds HA. Fairbanks LD, et al. J Chromatogr B Biomed Sci Appl. 1999 Sep 24;732(2):487-93. doi: 10.1016/s0378-4347(99)00303-5. J Chromatogr B Biomed Sci Appl. 1999. PMID: 10517371

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