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Functional classification of drugs by properties of their pairwise interactions.
Yeh P, Tschumi AI, Kishony R. Yeh P, et al. Among authors: kishony r. Nat Genet. 2006 Apr;38(4):489-94. doi: 10.1038/ng1755. Epub 2006 Mar 19. Nat Genet. 2006. PMID: 16550172
Modular epistasis in yeast metabolism.
Segrè D, Deluna A, Church GM, Kishony R. Segrè D, et al. Among authors: kishony r. Nat Genet. 2005 Jan;37(1):77-83. doi: 10.1038/ng1489. Epub 2004 Dec 12. Nat Genet. 2005. PMID: 15592468
An equivalence principle for the incorporation of favorable mutations in asexual populations.
Hegreness M, Shoresh N, Hartl D, Kishony R. Hegreness M, et al. Among authors: kishony r. Science. 2006 Mar 17;311(5767):1615-7. doi: 10.1126/science.1122469. Science. 2006. PMID: 16543462
Antibiotic interactions that select against resistance.
Chait R, Craney A, Kishony R. Chait R, et al. Among authors: kishony r. Nature. 2007 Apr 5;446(7136):668-71. doi: 10.1038/nature05685. Nature. 2007. PMID: 17410176
Exposing the fitness contribution of duplicated genes.
DeLuna A, Vetsigian K, Shoresh N, Hegreness M, Colón-González M, Chao S, Kishony R. DeLuna A, et al. Among authors: kishony r. Nat Genet. 2008 May;40(5):676-81. doi: 10.1038/ng.123. Epub 2008 Apr 13. Nat Genet. 2008. PMID: 18408719
Accelerated evolution of resistance in multidrug environments.
Hegreness M, Shoresh N, Damian D, Hartl D, Kishony R. Hegreness M, et al. Among authors: kishony r. Proc Natl Acad Sci U S A. 2008 Sep 16;105(37):13977-81. doi: 10.1073/pnas.0805965105. Epub 2008 Sep 8. Proc Natl Acad Sci U S A. 2008. PMID: 18779569 Free PMC article.
Drug interactions modulate the potential for evolution of resistance.
Michel JB, Yeh PJ, Chait R, Moellering RC Jr, Kishony R. Michel JB, et al. Among authors: kishony r. Proc Natl Acad Sci U S A. 2008 Sep 30;105(39):14918-23. doi: 10.1073/pnas.0800944105. Epub 2008 Sep 24. Proc Natl Acad Sci U S A. 2008. PMID: 18815368 Free PMC article.
Drug interactions and the evolution of antibiotic resistance.
Yeh PJ, Hegreness MJ, Aiden AP, Kishony R. Yeh PJ, et al. Among authors: kishony r. Nat Rev Microbiol. 2009 Jun;7(6):460-6. doi: 10.1038/nrmicro2133. Nat Rev Microbiol. 2009. PMID: 19444248 Free PMC article. Review.
Nonoptimal microbial response to antibiotics underlies suppressive drug interactions.
Bollenbach T, Quan S, Chait R, Kishony R. Bollenbach T, et al. Among authors: kishony r. Cell. 2009 Nov 13;139(4):707-18. doi: 10.1016/j.cell.2009.10.025. Cell. 2009. PMID: 19914165 Free PMC article.
Hydroxyurea triggers cellular responses that actively cause bacterial cell death.
Bollenbach T, Kishony R. Bollenbach T, et al. Among authors: kishony r. Mol Cell. 2009 Dec 11;36(5):728-9. doi: 10.1016/j.molcel.2009.11.027. Mol Cell. 2009. PMID: 20005834
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