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A functionally characterized test set of human induced pluripotent stem cells.
Boulting GL, Kiskinis E, Croft GF, Amoroso MW, Oakley DH, Wainger BJ, Williams DJ, Kahler DJ, Yamaki M, Davidow L, Rodolfa CT, Dimos JT, Mikkilineni S, MacDermott AB, Woolf CJ, Henderson CE, Wichterle H, Eggan K. Boulting GL, et al. Among authors: kiskinis e. Nat Biotechnol. 2011 Mar;29(3):279-86. doi: 10.1038/nbt.1783. Epub 2011 Feb 3. Nat Biotechnol. 2011. PMID: 21293464 Free PMC article.
Somatic coding mutations in human induced pluripotent stem cells.
Gore A, Li Z, Fung HL, Young JE, Agarwal S, Antosiewicz-Bourget J, Canto I, Giorgetti A, Israel MA, Kiskinis E, Lee JH, Loh YH, Manos PD, Montserrat N, Panopoulos AD, Ruiz S, Wilbert ML, Yu J, Kirkness EF, Izpisua Belmonte JC, Rossi DJ, Thomson JA, Eggan K, Daley GQ, Goldstein LS, Zhang K. Gore A, et al. Among authors: kiskinis e. Nature. 2011 Mar 3;471(7336):63-7. doi: 10.1038/nature09805. Nature. 2011. PMID: 21368825 Free PMC article.
Erosion of dosage compensation impacts human iPSC disease modeling.
Mekhoubad S, Bock C, de Boer AS, Kiskinis E, Meissner A, Eggan K. Mekhoubad S, et al. Among authors: kiskinis e. Cell Stem Cell. 2012 May 4;10(5):595-609. doi: 10.1016/j.stem.2012.02.014. Cell Stem Cell. 2012. PMID: 22560080 Free PMC article.
Axonal transport of TDP-43 mRNA granules is impaired by ALS-causing mutations.
Alami NH, Smith RB, Carrasco MA, Williams LA, Winborn CS, Han SSW, Kiskinis E, Winborn B, Freibaum BD, Kanagaraj A, Clare AJ, Badders NM, Bilican B, Chaum E, Chandran S, Shaw CE, Eggan KC, Maniatis T, Taylor JP. Alami NH, et al. Among authors: kiskinis e. Neuron. 2014 Feb 5;81(3):536-543. doi: 10.1016/j.neuron.2013.12.018. Neuron. 2014. PMID: 24507191 Free PMC article.
Pathways disrupted in human ALS motor neurons identified through genetic correction of mutant SOD1.
Kiskinis E, Sandoe J, Williams LA, Boulting GL, Moccia R, Wainger BJ, Han S, Peng T, Thams S, Mikkilineni S, Mellin C, Merkle FT, Davis-Dusenbery BN, Ziller M, Oakley D, Ichida J, Di Costanzo S, Atwater N, Maeder ML, Goodwin MJ, Nemesh J, Handsaker RE, Paull D, Noggle S, McCarroll SA, Joung JK, Woolf CJ, Brown RH, Eggan K. Kiskinis E, et al. Cell Stem Cell. 2014 Jun 5;14(6):781-95. doi: 10.1016/j.stem.2014.03.004. Epub 2014 Apr 3. Cell Stem Cell. 2014. PMID: 24704492 Free PMC article.
Genetic validation of a therapeutic target in a mouse model of ALS.
de Boer AS, Koszka K, Kiskinis E, Suzuki N, Davis-Dusenbery BN, Eggan K. de Boer AS, et al. Among authors: kiskinis e. Sci Transl Med. 2014 Aug 6;6(248):248ra104. doi: 10.1126/scitranslmed.3009351. Sci Transl Med. 2014. PMID: 25100738
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