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RAGE drives the development of glomerulosclerosis and implicates podocyte activation in the pathogenesis of diabetic nephropathy.
Wendt TM, Tanji N, Guo J, Kislinger TR, Qu W, Lu Y, Bucciarelli LG, Rong LL, Moser B, Markowitz GS, Stein G, Bierhaus A, Liliensiek B, Arnold B, Nawroth PP, Stern DM, D'Agati VD, Schmidt AM. Wendt TM, et al. Among authors: kislinger tr. Am J Pathol. 2003 Apr;162(4):1123-37. doi: 10.1016/S0002-9440(10)63909-0. Am J Pathol. 2003. PMID: 12651605 Free PMC article.
Receptor for advanced glycation end products mediates inflammation and enhanced expression of tissue factor in vasculature of diabetic apolipoprotein E-null mice.
Kislinger T, Tanji N, Wendt T, Qu W, Lu Y, Ferran LJ Jr, Taguchi A, Olson K, Bucciarelli L, Goova M, Hofmann MA, Cataldegirmen G, D'Agati V, Pischetsrieder M, Stern DM, Schmidt AM. Kislinger T, et al. Arterioscler Thromb Vasc Biol. 2001 Jun;21(6):905-10. doi: 10.1161/01.atv.21.6.905. Arterioscler Thromb Vasc Biol. 2001. PMID: 11397695
Blockade of RAGE-amphoterin signalling suppresses tumour growth and metastases.
Taguchi A, Blood DC, del Toro G, Canet A, Lee DC, Qu W, Tanji N, Lu Y, Lalla E, Fu C, Hofmann MA, Kislinger T, Ingram M, Lu A, Tanaka H, Hori O, Ogawa S, Stern DM, Schmidt AM. Taguchi A, et al. Nature. 2000 May 18;405(6784):354-60. doi: 10.1038/35012626. Nature. 2000. PMID: 10830965
159 results