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Methotrexate analogues. 12. Synthesis and biological properties of some aza homologues.
Martinelli JE, Chaykovsky M, Kisliuk RL, Gaumont Y, Gittelman MC. Martinelli JE, et al. Among authors: kisliuk rl. J Med Chem. 1979 Jul;22(7):869-74. doi: 10.1021/jm00193a022. J Med Chem. 1979. PMID: 109616
Aspects of the reversal of methotrexate toxicity in rodents.
Kisliuk RL, Tattersall MH, Gaumont Y, Pastore EJ, Brown B. Kisliuk RL, et al. Cancer Treat Rep. 1977 Jul;61(4):647-50. Cancer Treat Rep. 1977. PMID: 301779
Reduced derivatives of methotrexate.
Horwitz SB, Kisliuk RL. Horwitz SB, et al. Among authors: kisliuk rl. J Med Chem. 1968 Jul;11(4):907-8. doi: 10.1021/jm00310a055. J Med Chem. 1968. PMID: 5244347 No abstract available.
Studies on the antitumor effects of analogues of 5,8-dideazaisofolic acid and 5,8-dideazaisoaminopterin.
Hagan RL, Hynes JB, Pimsler M, Kisliuk RL. Hagan RL, et al. Among authors: kisliuk rl. Biochem Pharmacol. 1995 Sep 7;50(6):803-9. doi: 10.1016/0006-2952(95)00203-c. Biochem Pharmacol. 1995. PMID: 7575641
Folate analogues altered in the C9-N10 bridge region: N10-Toxylisohomofolic acid and N10-Toxylisohomoaminopterin.
Nair MG, O'Neal PC, Baugh CM, Kisliuk RL, Gaumont Y, Rodman M. Nair MG, et al. Among authors: kisliuk rl. J Med Chem. 1978 Jul;21(7):673-7. doi: 10.1021/jm00205a015. J Med Chem. 1978. PMID: 97383 No abstract available.
Synthesis and evaluation of 5-(arylthio)-9H-pyrimido[4,5-b]indole-2,4-diamines as receptor tyrosine kinase and thymidylate synthase inhibitors and as antitumor agents.
Zaware N, Kisliuk R, Bastian A, Ihnat MA, Gangjee A. Zaware N, et al. Bioorg Med Chem Lett. 2017 Apr 1;27(7):1602-1607. doi: 10.1016/j.bmcl.2017.02.018. Epub 2017 Feb 11. Bioorg Med Chem Lett. 2017. PMID: 28258797 Free PMC article.
Design, synthesis, and molecular modeling of novel pyrido[2,3-d]pyrimidine analogues as antifolates; application of Buchwald-Hartwig aminations of heterocycles.
Gangjee A, Namjoshi OA, Raghavan S, Queener SF, Kisliuk RL, Cody V. Gangjee A, et al. Among authors: kisliuk rl. J Med Chem. 2013 Jun 13;56(11):4422-41. doi: 10.1021/jm400086g. Epub 2013 May 21. J Med Chem. 2013. PMID: 23627352 Free PMC article.
Design, synthesis, biological evaluation and X-ray crystal structure of novel classical 6,5,6-tricyclic benzo[4,5]thieno[2,3-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors.
Zhang X, Zhou X, Kisliuk RL, Piraino J, Cody V, Gangjee A. Zhang X, et al. Among authors: kisliuk rl. Bioorg Med Chem. 2011 Jun 1;19(11):3585-94. doi: 10.1016/j.bmc.2011.03.067. Epub 2011 Apr 9. Bioorg Med Chem. 2011. PMID: 21550809 Free PMC article.
Single agents with designed combination chemotherapy potential: synthesis and evaluation of substituted pyrimido[4,5-b]indoles as receptor tyrosine kinase and thymidylate synthase inhibitors and as antitumor agents.
Gangjee A, Zaware N, Raghavan S, Ihnat M, Shenoy S, Kisliuk RL. Gangjee A, et al. Among authors: kisliuk rl. J Med Chem. 2010 Feb 25;53(4):1563-78. doi: 10.1021/jm9011142. J Med Chem. 2010. PMID: 20092323 Free PMC article.
2,4-Diamino-5-methyl-6-substituted arylthio-furo[2,3-d]pyrimidines as novel classical and nonclassical antifolates as potential dual thymidylate synthase and dihydrofolate reductase inhibitors.
Gangjee A, Jain HD, Phan J, Guo X, Queener SF, Kisliuk RL. Gangjee A, et al. Among authors: kisliuk rl. Bioorg Med Chem. 2010 Jan 15;18(2):953-61. doi: 10.1016/j.bmc.2009.11.029. Epub 2009 Dec 26. Bioorg Med Chem. 2010. PMID: 20056546 Free PMC article.
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