Kitani K - Search Results

1

The effect of a long term (6 months) treatment with (-)deprenyl on antioxidant enzyme activities in selective brain regions in old female Fischer 344 rats.

Carrillo MC, Kitani K, Kanai S, Sato Y, Miyasaka K, Ivy GO. Carrillo MC, et al. Among authors: kitani k. Biochem Pharmacol. 1994 Apr 20;47(8):1333-8. doi: 10.1016/0006-2952(94)90331-x. Biochem Pharmacol. 1994. PMID: 8185641

2

Effects of sanguiin H-6, a component of Sanguisorbae Radix, on lipopolysaccharide-stimulated nitric oxide production.

Yokozawa T, Chen CP, Tanaka T, Kitani K. Yokozawa T, et al. Among authors: kitani k. Biochem Pharmacol. 2002 Mar 1;63(5):853-8. doi: 10.1016/s0006-2952(01)00930-3. Biochem Pharmacol. 2002. PMID: 11911836

3

Dose-dependency of life span prolongation of F344/DuCrj rats injected with (-)deprenyl.

Kitani K, Kanai S, Miyasaka K, Carrillo MC, Ivy GO. Kitani K, et al. Biogerontology. 2005;6(5):297-302. doi: 10.1007/s10522-005-4804-4. Biogerontology. 2005. PMID: 16463106

4

Do antioxidant strategies work against aging and age-associated disorders? Propargylamines: a possible antioxidant strategy.

Kitani K, Minami C, Yamamoto T, Maruyama W, Kanai S, Ivy GO, Carrillo MC. Kitani K, et al. Ann N Y Acad Sci. 2001 Apr;928:248-60. doi: 10.1111/j.1749-6632.2001.tb05654.x. Ann N Y Acad Sci. 2001. PMID: 11795516 Review.

5

Common properties for propargylamines of enhancing superoxide dismutase and catalase activities in the dopaminergic system in the rat: implications for the life prolonging effect of (-)deprenyl.

Kitani K, Minami C, Maruyama W, Kanai S, Ivy GO, Carrillo MC. Kitani K, et al. J Neural Transm Suppl. 2000;(60):139-56. doi: 10.1007/978-3-7091-6301-6_9. J Neural Transm Suppl. 2000. PMID: 11205136

6

Assessing the effects of deprenyl on longevity and antioxidant defenses in different animal models.

Kitani K, Kanai S, Ivy GO, Carrillo MC. Kitani K, et al. Ann N Y Acad Sci. 1998 Nov 20;854:291-306. doi: 10.1111/j.1749-6632.1998.tb09910.x. Ann N Y Acad Sci. 1998. PMID: 9928438 Review.

7

Pharmacological interventions in aging and age-associated disorders: potentials of propargylamines for human use.

Kitani K, Minami C, Yamamoto T, Kanai S, Ivy GO, Carrillo MC. Kitani K, et al. Ann N Y Acad Sci. 2002 Apr;959:295-307. doi: 10.1111/j.1749-6632.2002.tb02101.x. Ann N Y Acad Sci. 2002. PMID: 11976204 Review.

8

The necessity of having a proper dose of (-)deprenyl (D) to prolong the life spans of rats explains discrepancies among different studies in the past.

Kitani K, Kanai S, Miyasaka K, Carrillo MC, Ivy GO. Kitani K, et al. Ann N Y Acad Sci. 2006 May;1067:375-82. doi: 10.1196/annals.1354.053. Ann N Y Acad Sci. 2006. PMID: 16804014

9

Neuroprotection by propargylamines in Parkinson's disease: suppression of apoptosis and induction of prosurvival genes.

Maruyama W, Akao Y, Carrillo MC, Kitani K, Youdium MB, Naoi M. Maruyama W, et al. Among authors: kitani k. Neurotoxicol Teratol. 2002 Sep-Oct;24(5):675-82. doi: 10.1016/s0892-0362(02)00221-0. Neurotoxicol Teratol. 2002. PMID: 12200198 Review.

10

Why (--)deprenyl prolongs survivals of experimental animals: increase of anti-oxidant enzymes in brain and other body tissues as well as mobilization of various humoral factors may lead to systemic anti-aging effects.

Kitani K, Minami C, Isobe K, Maehara K, Kanai S, Ivy GO, Carrillo MC. Kitani K, et al. Mech Ageing Dev. 2002 Apr 30;123(8):1087-100. doi: 10.1016/s0047-6374(01)00392-x. Mech Ageing Dev. 2002. PMID: 12044958 Review.

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