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The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis.
Imamura K, Izumi Y, Watanabe A, Tsukita K, Woltjen K, Yamamoto T, Hotta A, Kondo T, Kitaoka S, Ohta A, Tanaka A, Watanabe D, Morita M, Takuma H, Tamaoka A, Kunath T, Wray S, Furuya H, Era T, Makioka K, Okamoto K, Fujisawa T, Nishitoh H, Homma K, Ichijo H, Julien JP, Obata N, Hosokawa M, Akiyama H, Kaneko S, Ayaki T, Ito H, Kaji R, Takahashi R, Yamanaka S, Inoue H. Imamura K, et al. Among authors: kitaoka s. Sci Transl Med. 2017 May 24;9(391):eaaf3962. doi: 10.1126/scitranslmed.aaf3962. Sci Transl Med. 2017. PMID: 28539470 Free article.
Drug screening for ALS using patient-specific induced pluripotent stem cells.
Egawa N, Kitaoka S, Tsukita K, Naitoh M, Takahashi K, Yamamoto T, Adachi F, Kondo T, Okita K, Asaka I, Aoi T, Watanabe A, Yamada Y, Morizane A, Takahashi J, Ayaki T, Ito H, Yoshikawa K, Yamawaki S, Suzuki S, Watanabe D, Hioki H, Kaneko T, Makioka K, Okamoto K, Takuma H, Tamaoka A, Hasegawa K, Nonaka T, Hasegawa M, Kawata A, Yoshida M, Nakahata T, Takahashi R, Marchetto MC, Gage FH, Yamanaka S, Inoue H. Egawa N, et al. Among authors: kitaoka s. Sci Transl Med. 2012 Aug 1;4(145):145ra104. doi: 10.1126/scitranslmed.3004052. Sci Transl Med. 2012. PMID: 22855461
Response to comment on "Drug screening for ALS using patient-specific induced pluripotent stem cells".
Egawa N, Kitaoka S, Tsukita K, Naitoh M, Takahashi K, Yamamoto T, Adachi F, Kondo T, Okita K, Asaka I, Aoi T, Watanabe A, Yamada Y, Morizane A, Takahashi J, Ayaki T, Ito H, Yoshikawa K, Yamawaki S, Suzuki S, Watanabe D, Hioki H, Kaneko T, Makioka K, Okamoto K, Takuma H, Tamaoka A, Hasegawa K, Nonaka T, Hasegawa M, Kawata A, Yoshida M, Nakahata T, Takahashi R, Marchetto MC, Gage FH, Yamanaka S, Inoue H. Egawa N, et al. Among authors: kitaoka s. Sci Transl Med. 2013 Jun 5;5(188):188lr2. doi: 10.1126/scitranslmed.3005697. Sci Transl Med. 2013. PMID: 23740898
Modeling the early phenotype at the neuromuscular junction of spinal muscular atrophy using patient-derived iPSCs.
Yoshida M, Kitaoka S, Egawa N, Yamane M, Ikeda R, Tsukita K, Amano N, Watanabe A, Morimoto M, Takahashi J, Hosoi H, Nakahata T, Inoue H, Saito MK. Yoshida M, et al. Among authors: kitaoka s. Stem Cell Reports. 2015 Apr 14;4(4):561-8. doi: 10.1016/j.stemcr.2015.02.010. Epub 2015 Mar 19. Stem Cell Reports. 2015. PMID: 25801509 Free PMC article.
Thromboxane receptor activation enhances striatal dopamine release, leading to suppression of GABAergic transmission and enhanced sugar intake.
Mitsumori T, Furuyashiki T, Momiyama T, Nishi A, Shuto T, Hayakawa T, Ushikubi F, Kitaoka S, Aoki T, Inoue H, Matsuoka T, Narumiya S. Mitsumori T, et al. Among authors: kitaoka s. Eur J Neurosci. 2011 Aug;34(4):594-604. doi: 10.1111/j.1460-9568.2011.07774.x. Epub 2011 Jul 12. Eur J Neurosci. 2011. PMID: 21749493
PGE(2) -EP(2) signalling in endothelium is activated by haemodynamic stress and induces cerebral aneurysm through an amplifying loop via NF-κB.
Aoki T, Nishimura M, Matsuoka T, Yamamoto K, Furuyashiki T, Kataoka H, Kitaoka S, Ishibashi R, Ishibazawa A, Miyamoto S, Morishita R, Ando J, Hashimoto N, Nozaki K, Narumiya S. Aoki T, et al. Among authors: kitaoka s. Br J Pharmacol. 2011 Jul;163(6):1237-49. doi: 10.1111/j.1476-5381.2011.01358.x. Br J Pharmacol. 2011. PMID: 21426319 Free PMC article.
265 results