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Collagen IVα345 dysfunction in glomerular basement membrane diseases. I. Discovery of a COL4A3 variant in familial Goodpasture's and Alport diseases.
Pokidysheva EN, Seeger H, Pedchenko V, Chetyrkin S, Bergmann C, Abrahamson D, Cui ZW, Delpire E, Fervenza FC, Fidler AL, Fogo AB, Gaspert A, Grohmann M, Gross O, Haddad G, Harris RC, Kashtan C, Kitching AR, Lorenzen JM, McAdoo S, Pusey CD, Segelmark M, Simmons A, Voziyan PA, Wagner T, Wüthrich RP, Zhao MH, Boudko SP, Kistler AD, Hudson BG. Pokidysheva EN, et al. Among authors: kitching ar. J Biol Chem. 2021 Jan-Jun;296:100590. doi: 10.1016/j.jbc.2021.100590. Epub 2021 Mar 26. J Biol Chem. 2021. PMID: 33774048 Free PMC article.
IL-23, not IL-12, directs autoimmunity to the Goodpasture antigen.
Ooi JD, Phoon RK, Holdsworth SR, Kitching AR. Ooi JD, et al. Among authors: kitching ar. J Am Soc Nephrol. 2009 May;20(5):980-9. doi: 10.1681/ASN.2008080891. Epub 2009 Apr 8. J Am Soc Nephrol. 2009. PMID: 19357249 Free PMC article.
Molecular architecture of the Goodpasture autoantigen in anti-GBM nephritis.
Pedchenko V, Bondar O, Fogo AB, Vanacore R, Voziyan P, Kitching AR, Wieslander J, Kashtan C, Borza DB, Neilson EG, Wilson CB, Hudson BG. Pedchenko V, et al. Among authors: kitching ar. N Engl J Med. 2010 Jul 22;363(4):343-54. doi: 10.1056/NEJMoa0910500. N Engl J Med. 2010. PMID: 20660402 Free PMC article.
The HLA-DRB1*15:01-restricted Goodpasture's T cell epitope induces GN.
Ooi JD, Chang J, O'Sullivan KM, Pedchenko V, Hudson BG, Vandenbark AA, Fugger L, Holdsworth SR, Kitching AR. Ooi JD, et al. Among authors: kitching ar. J Am Soc Nephrol. 2013 Feb;24(3):419-31. doi: 10.1681/ASN.2012070705. Epub 2013 Feb 14. J Am Soc Nephrol. 2013. PMID: 23411782 Free PMC article.
T cell mediated autoimmune glomerular disease in mice.
Ooi JD, Gan PY, Odobasic D, Holdsworth SR, Kitching AR. Ooi JD, et al. Among authors: kitching ar. Curr Protoc Immunol. 2014 Nov 3;107:15.27.1-15.27.19. doi: 10.1002/0471142735.im1527s107. Curr Protoc Immunol. 2014. PMID: 25367126 Review.
Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells.
Ooi JD, Petersen J, Tan YH, Huynh M, Willett ZJ, Ramarathinam SH, Eggenhuizen PJ, Loh KL, Watson KA, Gan PY, Alikhan MA, Dudek NL, Handel A, Hudson BG, Fugger L, Power DA, Holt SG, Coates PT, Gregersen JW, Purcell AW, Holdsworth SR, La Gruta NL, Reid HH, Rossjohn J, Kitching AR. Ooi JD, et al. Among authors: kitching ar. Nature. 2017 May 11;545(7653):243-247. doi: 10.1038/nature22329. Epub 2017 May 3. Nature. 2017. PMID: 28467828 Free PMC article.
205 results