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Apolipoprotein E epsilon4 allele, elevated midlife total cholesterol level, and high midlife systolic blood pressure are independent risk factors for late-life Alzheimer disease.
Kivipelto M, Helkala EL, Laakso MP, Hänninen T, Hallikainen M, Alhainen K, Iivonen S, Mannermaa A, Tuomilehto J, Nissinen A, Soininen H. Kivipelto M, et al. Ann Intern Med. 2002 Aug 6;137(3):149-55. doi: 10.7326/0003-4819-137-3-200208060-00006. Ann Intern Med. 2002. PMID: 12160362
Memantine offers new possibilities for the treatment of VaD.
Winblad B, Kivipelto M. Winblad B, et al. Among authors: kivipelto m. Lancet Neurol. 2002 Dec;1(8):469. doi: 10.1016/s1474-4422(02)00232-6. Lancet Neurol. 2002. PMID: 12849324 Review. No abstract available.
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