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PPARĪ±-mediated responses in human adult liver stem cells: In vivo/in vitro and cross-species comparisons.
Kim S, Kiyosawa N, Burgoon LD, Chang CC, Zacharewski TR. Kim S, et al. Among authors: kiyosawa n. J Steroid Biochem Mol Biol. 2013 Nov;138:236-47. doi: 10.1016/j.jsbmb.2013.06.004. Epub 2013 Jun 27. J Steroid Biochem Mol Biol. 2013. PMID: 23811191
o,p'-DDT elicits PXR/CAR-, not ER-, mediated responses in the immature ovariectomized rat liver.
Kiyosawa N, Kwekel JC, Burgoon LD, Williams KJ, Tashiro C, Chittim B, Zacharewski TR. Kiyosawa N, et al. Toxicol Sci. 2008 Feb;101(2):350-63. doi: 10.1093/toxsci/kfm275. Epub 2007 Nov 5. Toxicol Sci. 2008. PMID: 17984292
Species-specific regulation of PXR/CAR/ER-target genes in the mouse and rat liver elicited by o, p'-DDT.
Kiyosawa N, Kwekel JC, Burgoon LD, Dere E, Williams KJ, Tashiro C, Chittim B, Zacharewski TR. Kiyosawa N, et al. BMC Genomics. 2008 Oct 16;9:487. doi: 10.1186/1471-2164-9-487. BMC Genomics. 2008. PMID: 18925944 Free PMC article.
Ethylene glycol monomethyl ether-induced toxicity is mediated through the inhibition of flavoprotein dehydrogenase enzyme family.
Takei M, Ando Y, Saitoh W, Tanimoto T, Kiyosawa N, Manabe S, Sanbuissho A, Okazaki O, Iwabuchi H, Yamoto T, Adam KP, Weiel JE, Ryals JA, Milburn MV, Guo L. Takei M, et al. Among authors: kiyosawa n. Toxicol Sci. 2010 Dec;118(2):643-52. doi: 10.1093/toxsci/kfq211. Epub 2010 Jul 8. Toxicol Sci. 2010. PMID: 20616209 Free PMC article.
Gene set-level network analysis using a toxicogenomics database.
Kiyosawa N, Manabe S, Sanbuissho A, Yamoto T. Kiyosawa N, et al. Genomics. 2010 Jul;96(1):39-49. doi: 10.1016/j.ygeno.2010.03.014. Epub 2010 Apr 2. Genomics. 2010. PMID: 20363313
Gene expression profiling in rat liver treated with various hepatotoxic-compounds inducing coagulopathy.
Hirode M, Omura K, Kiyosawa N, Uehara T, Shimuzu T, Ono A, Miyagishima T, Nagao T, Ohno Y, Urushidani T. Hirode M, et al. Among authors: kiyosawa n. J Toxicol Sci. 2009 Jun;34(3):281-93. doi: 10.2131/jts.34.281. J Toxicol Sci. 2009. PMID: 19483382
Toxicokintic and toxicodynamic analysis of clofibrate based on free drug concentrations in nagase analbuminemia rats (NAR).
Miida H, Arakawa S, Shibaya Y, Honda K, Kiyosawa N, Watanabe K, Manabe S, Takasaki W, Ueno K. Miida H, et al. Among authors: kiyosawa n. J Toxicol Sci. 2008 Aug;33(3):349-61. doi: 10.2131/jts.33.349. J Toxicol Sci. 2008. PMID: 18670166
Gene expression profiling of methapyrilene-induced hepatotoxicity in rat.
Uehara T, Kiyosawa N, Hirode M, Omura K, Shimizu T, Ono A, Mizukawa Y, Miyagishima T, Nagao T, Urushidani T. Uehara T, et al. Among authors: kiyosawa n. J Toxicol Sci. 2008 Feb;33(1):37-50. doi: 10.2131/jts.33.37. J Toxicol Sci. 2008. PMID: 18303183
Identification of glutathione depletion-responsive genes using phorone-treated rat liver.
Kiyosawa N, Uehara T, Gao W, Omura K, Hirode M, Shimizu T, Mizukawa Y, Ono A, Miyagishima T, Nagao T, Urushidani T. Kiyosawa N, et al. J Toxicol Sci. 2007 Dec;32(5):469-86. doi: 10.2131/jts.32.469. J Toxicol Sci. 2007. PMID: 18198479
Gene expression profiling of rat liver treated with serum triglyceride-decreasing compounds.
Omura K, Kiyosawa N, Uehara T, Hirode M, Shimizu T, Miyagishima T, Ono A, Nagao T, Urushidani T. Omura K, et al. Among authors: kiyosawa n. J Toxicol Sci. 2007 Oct;32(4):387-99. doi: 10.2131/jts.32.387. J Toxicol Sci. 2007. PMID: 17965553
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