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Effect of BF839 + earthworm protein supplement on motor and some non-motor symptoms of Parkinson's disease: a randomized clinical trial.
Zeng T, Lin C, Deng Y, Zhu W. Zeng T, et al. Front Neurol. 2024 Sep 6;15:1371791. doi: 10.3389/fneur.2024.1371791. eCollection 2024. Front Neurol. 2024. PMID: 39309265 Free PMC article.

RESULTS: From baseline to 12 weeks, compared with placebo, the trial group showed significant reductions in the United Parkinson's Disease Rate Scale (UPDRS) total score (-7.74 5.92 vs. -1.83 4.14, p < 0.001), UPDRS part I (-0.72 0.81 vs. -0.20 0.72, p = 0

…
RESULTS: From baseline to 12 weeks, compared with placebo, the trial group showed significant reductions in the United Parkinson's …
Diet and the gut microbiome in patients with Parkinson's disease.
Kwon D, Zhang K, Paul KC, Folle AD, Del Rosario I, Jacobs JP, Keener AM, Bronstein JM, Ritz B. Kwon D, et al. NPJ Parkinsons Dis. 2024 Apr 22;10(1):89. doi: 10.1038/s41531-024-00681-7. NPJ Parkinsons Dis. 2024. PMID: 38649365 Free PMC article.
It has been suggested that gut microbiota influence Parkinson's disease (PD) via the gut-brain axis. Here, we examine associations between diet and gut microbiome composition and its predicted functional pathways in patients with PD. ...Conversely, higher add …
It has been suggested that gut microbiota influence Parkinson's disease (PD) via the gut-brain axis. Here, we examine a …
Gut Microbiota and Its Repercussion in Parkinson's Disease: A Systematic Review in Occidental Patients.
Proano AC, Viteri JA, Orozco EN, Calle MA, Costa SC, Reyes DV, German-Montenegro M, Moncayo DF, Tobar AC, Moncayo JA. Proano AC, et al. Neurol Int. 2023 Jun 13;15(2):750-763. doi: 10.3390/neurolint15020047. Neurol Int. 2023. PMID: 37368331 Free PMC article. Review.
(1) Background: Parkinson's disease (PD) is a relatively common and complex pathology, and some of its mechanisms remain to be elucidated. ...This systematic review aims to gather existing data on the occidental hemisphere, compare it, and search for any sign …
(1) Background: Parkinson's disease (PD) is a relatively common and complex pathology, and some of its mechanisms remai …
Gut bacterial profiles in Parkinson's disease: A systematic review.
Li Z, Liang H, Hu Y, Lu L, Zheng C, Fan Y, Wu B, Zou T, Luo X, Zhang X, Zeng Y, Liu Z, Zhou Z, Yue Z, Ren Y, Li Z, Su Q, Xu P. Li Z, et al. CNS Neurosci Ther. 2023 Jan;29(1):140-157. doi: 10.1111/cns.13990. Epub 2022 Oct 25. CNS Neurosci Ther. 2023. PMID: 36284437 Free PMC article. Review.
INTRODUCTION: Recent advances have highlighted the relationships between gut dysbiosis and Parkinson's disease (PD). Microbiota transplantation from PD patients to mice can induce increased alpha-synuclein-mediated motor deficits. ...More than one report demo …
INTRODUCTION: Recent advances have highlighted the relationships between gut dysbiosis and Parkinson's disease (PD). Mi …
Specific gut microbiota alterations in essential tremor and its difference from Parkinson's disease.
Zhang P, Huang P, Du J, He Y, Liu J, He G, Cui S, Zhang W, Li G, Chen S. Zhang P, et al. NPJ Parkinsons Dis. 2022 Aug 5;8(1):98. doi: 10.1038/s41531-022-00359-y. NPJ Parkinsons Dis. 2022. PMID: 35931717 Free PMC article.
Essential tremor (ET) is the most common movement disorder and share overlapping symptoms with Parkinson's disease (PD), making differential diagnosis challenging. Gut dysbiosis is regarded crucial in the pathogenesis of PD. ...Clinical association results in …
Essential tremor (ET) is the most common movement disorder and share overlapping symptoms with Parkinson's disease (PD) …
Probiotics synergized with conventional regimen in managing Parkinson's disease.
Sun H, Zhao F, Liu Y, Ma T, Jin H, Quan K, Leng B, Zhao J, Yuan X, Li Z, Li F, Kwok LY, Zhang S, Sun Z, Zhang J, Zhang H. Sun H, et al. NPJ Parkinsons Dis. 2022 May 24;8(1):62. doi: 10.1038/s41531-022-00327-6. NPJ Parkinsons Dis. 2022. PMID: 35610236 Free PMC article.
Parkinson's disease (PD) is mainly managed by pharmacological therapy (e.g., Benserazide and dopamine agonists). ...Klebsiella oxytoca correlated negatively with feces hardness. Moreover, co-administering Probio-M8 increased SGBs involved in tryptophan …
Parkinson's disease (PD) is mainly managed by pharmacological therapy (e.g., Benserazide and dopamine agonists). ... …
Potential cannabidiol (CBD) repurposing as antibacterial and promising therapy of CBD plus polymyxin B (PB) against PB-resistant gram-negative bacilli.
Abichabki N, Zacharias LV, Moreira NC, Bellissimo-Rodrigues F, Moreira FL, Benzi JRL, Ogasawara TMC, Ferreira JC, Ribeiro CM, Pavan FR, Pereira LRL, Brancini GTP, Braga GÚL, Zuardi AW, Hallak JEC, Crippa JAS, Lanchote VL, Cantón R, Darini ALC, Andrade LN. Abichabki N, et al. Sci Rep. 2022 Apr 19;12(1):6454. doi: 10.1038/s41598-022-10393-8. Sci Rep. 2022. PMID: 35440801 Free PMC article.
For most of the GNB studied, our results showed that low concentrations of PB ( 2 g/mL) allow CBD ( 4 g/mL) to exert antibacterial activity against GNB (e.g., Klebsiella pneumoniae, Escherichia coli, Acinetobacter baumannii), including PB-resistant GNB. ...
For most of the GNB studied, our results showed that low concentrations of PB ( 2 g/mL) allow CBD ( 4 g/mL) to exert antibacterial activity …
The small bowel microbiome changes significantly with age and aspects of the ageing process.
Leite G, Pimentel M, Barlow GM, Mathur R. Leite G, et al. Microb Cell. 2021 Dec 27;9(1):21-23. doi: 10.15698/mic2022.01.768. eCollection 2022 Jan 3. Microb Cell. 2021. PMID: 35083314 Free PMC article.
Gut microbiome changes have been associated with human ageing and implicated in age-related diseases including Alzheimer's disease and Parkinson's disease. However, studies to date have used stool samples, which do not represent the entire gut. ...Diff …
Gut microbiome changes have been associated with human ageing and implicated in age-related diseases including Alzheimer's disease an …
Cross-Sectional Study on the Gut Microbiome of Parkinson's Disease Patients in Central China.
Mao L, Zhang Y, Tian J, Sang M, Zhang G, Zhou Y, Wang P. Mao L, et al. Front Microbiol. 2021 Sep 28;12:728479. doi: 10.3389/fmicb.2021.728479. eCollection 2021. Front Microbiol. 2021. PMID: 34650532 Free PMC article.
Gastrointestinal dysfunction plays an important role in the occurrence and development of Parkinson's disease (PD). This study investigates the composition of the gut microbiome using shotgun metagenomic sequencing in PD patients in central China. ...Further …
Gastrointestinal dysfunction plays an important role in the occurrence and development of Parkinson's disease (PD). Thi …
20 results