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Mechanisms of the intestinal effects of dietary fats and milk products on colon carcinogenesis.
Van der Meer R, Lapré JA, Govers MJ, Kleibeuker JH. Van der Meer R, et al. Among authors: kleibeuker jh. Cancer Lett. 1997 Mar 19;114(1-2):75-83. doi: 10.1016/s0304-3835(97)04629-6. Cancer Lett. 1997. PMID: 9103258 Review.
Cytotoxicity of rhein, the active metabolite of sennoside laxatives, is reduced by multidrug resistance-associated protein 1.
van Gorkom BA, Timmer-Bosscha H, de Jong S, van der Kolk DM, Kleibeuker JH, de Vries EG. van Gorkom BA, et al. Among authors: kleibeuker jh. Br J Cancer. 2002 May 6;86(9):1494-500. doi: 10.1038/sj.bjc.6600255. Br J Cancer. 2002. PMID: 11986786 Free PMC article.
Calcium affects biomarkers of colon carcinogenesis after right hemicolectomy.
van Gorkom BA, van der Meer R, Karrenbeld A, van der Sluis T, Zwart N, Termont DS, Boersma-van Ek W, de Vries EG, Kleibeuker JH. van Gorkom BA, et al. Among authors: kleibeuker jh. Eur J Clin Invest. 2002 Sep;32(9):693-9. doi: 10.1046/j.1365-2362.2002.01048.x. Eur J Clin Invest. 2002. PMID: 12486870 Clinical Trial.
Red meat and colon cancer: dietary haem-induced colonic cytotoxicity and epithelial hyperproliferation are inhibited by calcium.
Sesink AL, Termont DS, Kleibeuker JH, Van der Meer R. Sesink AL, et al. Among authors: kleibeuker jh. Carcinogenesis. 2001 Oct;22(10):1653-9. doi: 10.1093/carcin/22.10.1653. Carcinogenesis. 2001. PMID: 11577005
Red meat and colon cancer: dietary haem, but not fat, has cytotoxic and hyperproliferative effects on rat colonic epithelium.
Sesink AL, Termont DS, Kleibeuker JH, Van Der Meer R. Sesink AL, et al. Among authors: kleibeuker jh. Carcinogenesis. 2000 Oct;21(10):1909-15. doi: 10.1093/carcin/21.10.1909. Carcinogenesis. 2000. PMID: 11023550
Red meat and colon cancer: the cytotoxic and hyperproliferative effects of dietary heme.
Sesink AL, Termont DS, Kleibeuker JH, Van der Meer R. Sesink AL, et al. Among authors: kleibeuker jh. Cancer Res. 1999 Nov 15;59(22):5704-9. Cancer Res. 1999. PMID: 10582688
Effects of hemicolectomy on bile acid metabolism in relation to colon carcinogenesis in man.
van Gorkom BA, Cats A, van der Meer R, Kuipers F, Verschueren RC, Mulder NH, de Vries EG, Kleibeuker JH. van Gorkom BA, et al. Among authors: kleibeuker jh. Eur J Clin Invest. 1997 Jul;27(7):589-94. doi: 10.1046/j.1365-2362.1997.1440693.x. Eur J Clin Invest. 1997. PMID: 9263747
Calcium in milk products precipitates intestinal fatty acids and secondary bile acids and thus inhibits colonic cytotoxicity in humans.
Govers MJ, Termont DS, Lapré JA, Kleibeuker JH, Vonk RJ, Van der Meer R. Govers MJ, et al. Among authors: kleibeuker jh. Cancer Res. 1996 Jul 15;56(14):3270-5. Cancer Res. 1996. PMID: 8764120 Clinical Trial.
Increased epithelial cell proliferation in the colon of patients with acromegaly.
Cats A, Dullaart RP, Kleibeuker JH, Kuipers F, Sluiter WJ, Hardonk MJ, de Vries EG. Cats A, et al. Among authors: kleibeuker jh. Cancer Res. 1996 Feb 1;56(3):523-6. Cancer Res. 1996. PMID: 8564965
Epithelial cell proliferation in the sigmoid colon of patients with adenomatous polyps increases during oral calcium supplementation.
Kleibeuker JH, Welberg JW, Mulder NH, van der Meer R, Cats A, Limburg AJ, Kreumer WM, Hardonk MJ, de Vries EG. Kleibeuker JH, et al. Br J Cancer. 1993 Mar;67(3):500-3. doi: 10.1038/bjc.1993.93. Br J Cancer. 1993. PMID: 8439500 Free PMC article.
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