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Replication timing maintains the global epigenetic state in human cells.
Klein KN, Zhao PA, Lyu X, Sasaki T, Bartlett DA, Singh AM, Tasan I, Zhang M, Watts LP, Hiraga SI, Natsume T, Zhou X, Baslan T, Leung D, Kanemaki MT, Donaldson AD, Zhao H, Dalton S, Corces VG, Gilbert DM. Klein KN, et al. Science. 2021 Apr 23;372(6540):371-378. doi: 10.1126/science.aba5545. Epub 2021 Apr 22. Science. 2021. PMID: 33888635 Free PMC article.
Emergence of replication timing during early mammalian development.
Nakatani T, Schauer T, Altamirano-Pacheco L, Klein KN, Ettinger A, Pal M, Gilbert DM, Torres-Padilla ME. Nakatani T, et al. Among authors: klein kn. Nature. 2024 Jan;625(7994):401-409. doi: 10.1038/s41586-023-06872-1. Epub 2023 Dec 20. Nature. 2024. PMID: 38123678 Free PMC article.
RIF1 regulates early replication timing in murine B cells.
Malzl D, Peycheva M, Rahjouei A, Gnan S, Klein KN, Nazarova M, Schoeberl UE, Gilbert DM, Buonomo SCB, Di Virgilio M, Neumann T, Pavri R. Malzl D, et al. Among authors: klein kn. Nat Commun. 2023 Dec 11;14(1):8049. doi: 10.1038/s41467-023-43778-y. Nat Commun. 2023. PMID: 38081811 Free PMC article.
Cohesin-mediated loop anchors confine the locations of human replication origins.
Emerson DJ, Zhao PA, Cook AL, Barnett RJ, Klein KN, Saulebekova D, Ge C, Zhou L, Simandi Z, Minsk MK, Titus KR, Wang W, Gong W, Zhang D, Yang L, Venev SV, Gibcus JH, Yang H, Sasaki T, Kanemaki MT, Yue F, Dekker J, Chen CL, Gilbert DM, Phillips-Cremins JE. Emerson DJ, et al. Among authors: klein kn. Nature. 2022 Jun;606(7915):812-819. doi: 10.1038/s41586-022-04803-0. Epub 2022 Jun 8. Nature. 2022. PMID: 35676475 Free PMC article.
Soto CJ, Zhao PA, Klein KN, Gilbert DM, Srivastava A. Soto CJ, et al. Among authors: klein kn. Proc IEEE Int Symp Biomed Imaging. 2021 Apr;2021:788-791. doi: 10.1109/isbi48211.2021.9433812. Epub 2021 May 25. Proc IEEE Int Symp Biomed Imaging. 2021. PMID: 35165532 Free PMC article.
Catalytically Enhanced Cas9 through Directed Protein Evolution.
Hand TH, Roth MO, Smith CL, Shiel E, Klein KN, Gilbert DM, Li H. Hand TH, et al. Among authors: klein kn. CRISPR J. 2021 Apr;4(2):223-232. doi: 10.1089/crispr.2020.0092. CRISPR J. 2021. PMID: 33876948 Free PMC article.
Cohesin depleted cells rebuild functional nuclear compartments after endomitosis.
Cremer M, Brandstetter K, Maiser A, Rao SSP, Schmid VJ, Guirao-Ortiz M, Mitra N, Mamberti S, Klein KN, Gilbert DM, Leonhardt H, Cardoso MC, Aiden EL, Harz H, Cremer T. Cremer M, et al. Among authors: klein kn. Nat Commun. 2020 Dec 1;11(1):6146. doi: 10.1038/s41467-020-19876-6. Nat Commun. 2020. PMID: 33262376 Free PMC article.
Identifying cis Elements for Spatiotemporal Control of Mammalian DNA Replication.
Sima J, Chakraborty A, Dileep V, Michalski M, Klein KN, Holcomb NP, Turner JL, Paulsen MT, Rivera-Mulia JC, Trevilla-Garcia C, Bartlett DA, Zhao PA, Washburn BK, Nora EP, Kraft K, Mundlos S, Bruneau BG, Ljungman M, Fraser P, Ay F, Gilbert DM. Sima J, et al. Among authors: klein kn. Cell. 2019 Feb 7;176(4):816-830.e18. doi: 10.1016/j.cell.2018.11.036. Epub 2018 Dec 27. Cell. 2019. PMID: 30595451 Free PMC article.
Replication timing alterations in leukemia affect clinically relevant chromosome domains.
Rivera-Mulia JC, Sasaki T, Trevilla-Garcia C, Nakamichi N, Knapp DJHF, Hammond CA, Chang BH, Tyner JW, Devidas M, Zimmerman J, Klein KN, Somasundaram V, Druker BJ, Gruber TA, Koren A, Eaves CJ, Gilbert DM. Rivera-Mulia JC, et al. Among authors: klein kn. Blood Adv. 2019 Nov 12;3(21):3201-3213. doi: 10.1182/bloodadvances.2019000641. Blood Adv. 2019. PMID: 31698451 Free PMC article.
12 results