Klein U - Search Results

1

Cellular origin of human B-cell lymphomas.

Küppers R, Klein U, Hansmann ML, Rajewsky K. Küppers R, et al. Among authors: klein u. N Engl J Med. 1999 Nov 11;341(20):1520-9. doi: 10.1056/NEJM199911113412007. N Engl J Med. 1999. PMID: 10559454 Review. No abstract available.

2

Receptor revision plays no major role in shaping the receptor repertoire of human memory B cells after the onset of somatic hypermutation.

Goossens T, Bräuninger A, Klein U, Küppers R, Rajewsky K. Goossens T, et al. Among authors: klein u. Eur J Immunol. 2001 Dec;31(12):3638-48. doi: 10.1002/1521-4141(200112)31:12<3638::aid-immu3638>3.0.co;2-g. Eur J Immunol. 2001. PMID: 11745384

3

Mice reconstituted with DNA polymerase beta-deficient fetal liver cells are able to mount a T cell-dependent immune response and mutate their Ig genes normally.

Esposito G, Texido G, Betz UA, Gu H, Müller W, Klein U, Rajewsky K. Esposito G, et al. Among authors: klein u. Proc Natl Acad Sci U S A. 2000 Feb 1;97(3):1166-71. doi: 10.1073/pnas.97.3.1166. Proc Natl Acad Sci U S A. 2000. PMID: 10655502 Free PMC article.

4

The role of somatic hypermutation in the generation of deletions and duplications in human Ig V region genes and chromosomal translocations.

Küppers R, Goossens T, Klein U. Küppers R, et al. Among authors: klein u. Curr Top Microbiol Immunol. 1999;246:193-8. doi: 10.1007/978-3-642-60162-0_24. Curr Top Microbiol Immunol. 1999. PMID: 10396056 Review. No abstract available.

5

Phenotypic and molecular characterization of human peripheral blood B-cell subsets with special reference to N-region addition and J kappa-usage in V kappa J kappa-joints and kappa/lambda-ratios in naive versus memory B-cell subsets to identify traces of receptor editing processes.

Klein U, Rajewsky K, Küppers R. Klein U, et al. Curr Top Microbiol Immunol. 1999;246:141-6; discussion 147. doi: 10.1007/978-3-642-60162-0_18. Curr Top Microbiol Immunol. 1999. PMID: 10396050

6

Human immunoglobulin (Ig)M+IgD+ peripheral blood B cells expressing the CD27 cell surface antigen carry somatically mutated variable region genes: CD27 as a general marker for somatically mutated (memory) B cells.

Klein U, Rajewsky K, Küppers R. Klein U, et al. J Exp Med. 1998 Nov 2;188(9):1679-89. doi: 10.1084/jem.188.9.1679. J Exp Med. 1998. PMID: 9802980 Free PMC article.

7

Somatic hypermutation in normal and transformed human B cells.

Klein U, Goossens T, Fischer M, Kanzler H, Braeuninger A, Rajewsky K, Küppers R. Klein U, et al. Immunol Rev. 1998 Apr;162:261-80. doi: 10.1111/j.1600-065x.1998.tb01447.x. Immunol Rev. 1998. PMID: 9602370 Review.

8

Frequent occurrence of deletions and duplications during somatic hypermutation: implications for oncogene translocations and heavy chain disease.

Goossens T, Klein U, Küppers R. Goossens T, et al. Among authors: klein u. Proc Natl Acad Sci U S A. 1998 Mar 3;95(5):2463-8. doi: 10.1073/pnas.95.5.2463. Proc Natl Acad Sci U S A. 1998. PMID: 9482908 Free PMC article.

9

Molecular single-cell analysis reveals that CD5-positive peripheral blood B cells in healthy humans are characterized by rearranged Vkappa genes lacking somatic mutation.

Fischer M, Klein U, Küppers R. Fischer M, et al. Among authors: klein u. J Clin Invest. 1997 Oct 1;100(7):1667-76. doi: 10.1172/JCI119691. J Clin Invest. 1997. PMID: 9312164 Free PMC article.

10

Evidence for a large compartment of IgM-expressing memory B cells in humans.

Klein U, Küppers R, Rajewsky K. Klein U, et al. Blood. 1997 Feb 15;89(4):1288-98. Blood. 1997. PMID: 9028952

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