Klein-Szanto AJ - Search Results

1

Elk-1 phosphorylated at threonine-417 is present in diverse cancers and correlates with differentiation grade of colonic adenocarcinoma.

Morris JF, Sul JY, Kim MS, Klein-Szanto AJ, Schochet T, Rustgi A, Eberwine JH. Morris JF, et al. Hum Pathol. 2013 May;44(5):766-76. doi: 10.1016/j.humpath.2012.08.001. Epub 2012 Oct 29. Hum Pathol. 2013. PMID: 23114923 Free PMC article.

2

AKT induces senescence in primary esophageal epithelial cells but is permissive for differentiation as revealed in organotypic culture.

Oyama K, Okawa T, Nakagawa H, Takaoka M, Andl CD, Kim SH, Klein-Szanto A, Diehl JA, Herlyn M, El-Deiry W, Rustgi AK. Oyama K, et al. Oncogene. 2007 Apr 5;26(16):2353-64. doi: 10.1038/sj.onc.1210025. Epub 2006 Oct 9. Oncogene. 2007. PMID: 17043653 Free PMC article.

3

Coordinated functions of E-cadherin and transforming growth factor beta receptor II in vitro and in vivo.

Andl CD, Fargnoli BB, Okawa T, Bowser M, Takaoka M, Nakagawa H, Klein-Szanto A, Hua X, Herlyn M, Rustgi AK. Andl CD, et al. Cancer Res. 2006 Oct 15;66(20):9878-85. doi: 10.1158/0008-5472.CAN-05-4157. Cancer Res. 2006. PMID: 17047049 Free PMC article.

4

The functional interplay between EGFR overexpression, hTERT activation, and p53 mutation in esophageal epithelial cells with activation of stromal fibroblasts induces tumor development, invasion, and differentiation.

Okawa T, Michaylira CZ, Kalabis J, Stairs DB, Nakagawa H, Andl CD, Johnstone CN, Klein-Szanto AJ, El-Deiry WS, Cukierman E, Herlyn M, Rustgi AK. Okawa T, et al. Genes Dev. 2007 Nov 1;21(21):2788-803. doi: 10.1101/gad.1544507. Genes Dev. 2007. PMID: 17974918 Free PMC article.

5

Bortezomib induces apoptosis in esophageal squamous cell carcinoma cells through activation of the p38 mitogen-activated protein kinase pathway.

Lioni M, Noma K, Snyder A, Klein-Szanto A, Diehl JA, Rustgi AK, Herlyn M, Smalley KS. Lioni M, et al. Mol Cancer Ther. 2008 Sep;7(9):2866-75. doi: 10.1158/1535-7163.MCT-08-0391. Mol Cancer Ther. 2008. PMID: 18790767 Free PMC article.

6

Cdx1 and c-Myc foster the initiation of transdifferentiation of the normal esophageal squamous epithelium toward Barrett's esophagus.

Stairs DB, Nakagawa H, Klein-Szanto A, Mitchell SD, Silberg DG, Tobias JW, Lynch JP, Rustgi AK. Stairs DB, et al. PLoS One. 2008;3(10):e3534. doi: 10.1371/journal.pone.0003534. Epub 2008 Oct 27. PLoS One. 2008. PMID: 18953412 Free PMC article.

7

Epidermal growth factor receptor and mutant p53 expand an esophageal cellular subpopulation capable of epithelial-to-mesenchymal transition through ZEB transcription factors.

Ohashi S, Natsuizaka M, Wong GS, Michaylira CZ, Grugan KD, Stairs DB, Kalabis J, Vega ME, Kalman RA, Nakagawa M, Klein-Szanto AJ, Herlyn M, Diehl JA, Rustgi AK, Nakagawa H. Ohashi S, et al. Cancer Res. 2010 May 15;70(10):4174-84. doi: 10.1158/0008-5472.CAN-09-4614. Epub 2010 Apr 27. Cancer Res. 2010. PMID: 20424117 Free PMC article.

8

Periostin, a cell adhesion molecule, facilitates invasion in the tumor microenvironment and annotates a novel tumor-invasive signature in esophageal cancer.

Michaylira CZ, Wong GS, Miller CG, Gutierrez CM, Nakagawa H, Hammond R, Klein-Szanto AJ, Lee JS, Kim SB, Herlyn M, Diehl JA, Gimotty P, Rustgi AK. Michaylira CZ, et al. Cancer Res. 2010 Jul 1;70(13):5281-92. doi: 10.1158/0008-5472.CAN-10-0704. Epub 2010 Jun 1. Cancer Res. 2010. PMID: 20516120 Free PMC article.

9

Fibroblast-secreted hepatocyte growth factor plays a functional role in esophageal squamous cell carcinoma invasion.

Grugan KD, Miller CG, Yao Y, Michaylira CZ, Ohashi S, Klein-Szanto AJ, Diehl JA, Herlyn M, Han M, Nakagawa H, Rustgi AK. Grugan KD, et al. Proc Natl Acad Sci U S A. 2010 Jun 15;107(24):11026-31. doi: 10.1073/pnas.0914295107. Epub 2010 Jun 1. Proc Natl Acad Sci U S A. 2010. PMID: 20534479 Free PMC article.

10

Deletion of p120-catenin results in a tumor microenvironment with inflammation and cancer that establishes it as a tumor suppressor gene.

Stairs DB, Bayne LJ, Rhoades B, Vega ME, Waldron TJ, Kalabis J, Klein-Szanto A, Lee JS, Katz JP, Diehl JA, Reynolds AB, Vonderheide RH, Rustgi AK. Stairs DB, et al. Cancer Cell. 2011 Apr 12;19(4):470-83. doi: 10.1016/j.ccr.2011.02.007. Cancer Cell. 2011. PMID: 21481789 Free PMC article.

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