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78 results
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IGF-I: an essential factor in terminal end bud formation and ductal morphogenesis.
Kleinberg DL, Feldman M, Ruan W. Kleinberg DL, et al. J Mammary Gland Biol Neoplasia. 2000 Jan;5(1):7-17. doi: 10.1023/a:1009507030633. J Mammary Gland Biol Neoplasia. 2000. PMID: 10791764 Review.
Lipid metabolism in phosphatidylinositol transfer protein alpha-deficient vibrator mice.
Monaco ME, Kim J, Ruan W, Wieczorek R, Kleinberg DL, Walden PD. Monaco ME, et al. Among authors: kleinberg dl. Biochem Biophys Res Commun. 2004 Apr 30;317(2):444-50. doi: 10.1016/j.bbrc.2004.03.054. Biochem Biophys Res Commun. 2004. PMID: 15063778
IGF-I, GH, and sex steroid effects in normal mammary gland development.
Kleinberg DL, Ruan W. Kleinberg DL, et al. J Mammary Gland Biol Neoplasia. 2008 Dec;13(4):353-60. doi: 10.1007/s10911-008-9103-7. Epub 2008 Nov 25. J Mammary Gland Biol Neoplasia. 2008. PMID: 19034633
Pasireotide, an IGF-I action inhibitor, prevents growth hormone and estradiol-induced mammary hyperplasia.
Kleinberg DL, Ameri P, Singh B. Kleinberg DL, et al. Pituitary. 2011 Mar;14(1):44-52. doi: 10.1007/s11102-010-0257-0. Pituitary. 2011. PMID: 20890664
Growth hormone and insulin-like growth factor-I in the transition from normal mammary development to preneoplastic mammary lesions.
Kleinberg DL, Wood TL, Furth PA, Lee AV. Kleinberg DL, et al. Endocr Rev. 2009 Feb;30(1):51-74. doi: 10.1210/er.2008-0022. Epub 2008 Dec 15. Endocr Rev. 2009. PMID: 19075184 Free PMC article. Review.
Insulin-like growth factor (IGF)-I controls prostate fibromuscular development: IGF-I inhibition prevents both fibromuscular and glandular development in eugonadal mice.
Kleinberg DL, Ruan W, Yee D, Kovacs KT, Vidal S. Kleinberg DL, et al. Endocrinology. 2007 Mar;148(3):1080-8. doi: 10.1210/en.2006-1272. Epub 2006 Nov 30. Endocrinology. 2007. PMID: 17138659
Progesterone stimulates mammary gland ductal morphogenesis by synergizing with and enhancing insulin-like growth factor-I action.
Ruan W, Monaco ME, Kleinberg DL. Ruan W, et al. Among authors: kleinberg dl. Endocrinology. 2005 Mar;146(3):1170-8. doi: 10.1210/en.2004-1360. Epub 2004 Dec 16. Endocrinology. 2005. PMID: 15604210
SOM230 inhibits insulin-like growth factor-I action in mammary gland development by pituitary independent mechanism: mediated through somatostatin subtype receptor 3?
Ruan W, Fahlbusch F, Clemmons DR, Monaco ME, Walden PD, Silva AP, Schmid HA, Kleinberg DL. Ruan W, et al. Among authors: kleinberg dl. Mol Endocrinol. 2006 Feb;20(2):426-36. doi: 10.1210/me.2005-0283. Epub 2005 Oct 13. Mol Endocrinol. 2006. PMID: 16223973
Moderate doses of hGH (0.64 mg/d) improve lipids but not cardiovascular function in GH-deficient adults with normal baseline cardiac function.
Newman CB, Frisch KA, Rosenzweig B, Roubenoff R, Rey M, Kidder T, Kong Y, Pursnani A, Sedlis SP, Schwartzbard A, Kleinberg DL. Newman CB, et al. Among authors: kleinberg dl. J Clin Endocrinol Metab. 2011 Jan;96(1):122-32. doi: 10.1210/jc.2010-1204. Epub 2010 Oct 6. J Clin Endocrinol Metab. 2011. PMID: 20926529 Clinical Trial.
The pivotal role of insulin-like growth factor I in normal mammary development.
Kleinberg DL, Barcellos-Hoff MH. Kleinberg DL, et al. Endocrinol Metab Clin North Am. 2011 Sep;40(3):461-71, vii. doi: 10.1016/j.ecl.2011.06.001. Endocrinol Metab Clin North Am. 2011. PMID: 21889714 Review.
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