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Selection of small peptides, inhibitors of translation.
Llano-Sotelo B, Klepacki D, Mankin AS. Llano-Sotelo B, et al. Among authors: klepacki d. J Mol Biol. 2009 Sep 4;391(5):813-9. doi: 10.1016/j.jmb.2009.06.069. Epub 2009 Jul 2. J Mol Biol. 2009. PMID: 19576904 Free PMC article.
The structure of ribosome-lankacidin complex reveals ribosomal sites for synergistic antibiotics.
Auerbach T, Mermershtain I, Davidovich C, Bashan A, Belousoff M, Wekselman I, Zimmerman E, Xiong L, Klepacki D, Arakawa K, Kinashi H, Mankin AS, Yonath A. Auerbach T, et al. Among authors: klepacki d. Proc Natl Acad Sci U S A. 2010 Feb 2;107(5):1983-8. doi: 10.1073/pnas.0914100107. Epub 2010 Jan 11. Proc Natl Acad Sci U S A. 2010. PMID: 20080686 Free PMC article.
Role of antibiotic ligand in nascent peptide-dependent ribosome stalling.
Vázquez-Laslop N, Klepacki D, Mulhearn DC, Ramu H, Krasnykh O, Franzblau S, Mankin AS. Vázquez-Laslop N, et al. Among authors: klepacki d. Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):10496-501. doi: 10.1073/pnas.1103474108. Epub 2011 Jun 13. Proc Natl Acad Sci U S A. 2011. PMID: 21670252 Free PMC article.
Interactions of the TnaC nascent peptide with rRNA in the exit tunnel enable the ribosome to respond to free tryptophan.
Martínez AK, Gordon E, Sengupta A, Shirole N, Klepacki D, Martinez-Garriga B, Brown LM, Benedik MJ, Yanofsky C, Mankin AS, Vazquez-Laslop N, Sachs MS, Cruz-Vera LR. Martínez AK, et al. Among authors: klepacki d. Nucleic Acids Res. 2014 Jan;42(2):1245-56. doi: 10.1093/nar/gkt923. Epub 2013 Oct 16. Nucleic Acids Res. 2014. PMID: 24137004 Free PMC article.
45 results