Kliewer SA - Search Results

1

PXR, CAR and drug metabolism.

Willson TM, Kliewer SA. Willson TM, et al. Among authors: kliewer sa. Nat Rev Drug Discov. 2002 Apr;1(4):259-66. doi: 10.1038/nrd753. Nat Rev Drug Discov. 2002. PMID: 12120277 Review.

2

Structural basis of human pregnane X receptor activation by the hops constituent colupulone.

Teotico DG, Bischof JJ, Peng L, Kliewer SA, Redinbo MR. Teotico DG, et al. Among authors: kliewer sa. Mol Pharmacol. 2008 Dec;74(6):1512-20. doi: 10.1124/mol.108.050732. Epub 2008 Sep 2. Mol Pharmacol. 2008. PMID: 18768384 Free PMC article.

3

The nuclear pregnane X receptor regulates xenobiotic detoxification.

Kliewer SA. Kliewer SA. J Nutr. 2003 Jul;133(7 Suppl):2444S-2447S. doi: 10.1093/jn/133.7.2444S. J Nutr. 2003. PMID: 12840222 Review.

4

Crystal structure of the pregnane X receptor-estradiol complex provides insights into endobiotic recognition.

Xue Y, Moore LB, Orans J, Peng L, Bencharit S, Kliewer SA, Redinbo MR. Xue Y, et al. Among authors: kliewer sa. Mol Endocrinol. 2007 May;21(5):1028-38. doi: 10.1210/me.2006-0323. Epub 2007 Feb 27. Mol Endocrinol. 2007. PMID: 17327420

5

The nuclear xenobiotic receptor CAR: structural determinants of constitutive activation and heterodimerization.

Suino K, Peng L, Reynolds R, Li Y, Cha JY, Repa JJ, Kliewer SA, Xu HE. Suino K, et al. Among authors: kliewer sa. Mol Cell. 2004 Dec 22;16(6):893-905. doi: 10.1016/j.molcel.2004.11.036. Mol Cell. 2004. PMID: 15610733

6

Structural disorder in the complex of human pregnane X receptor and the macrolide antibiotic rifampicin.

Chrencik JE, Orans J, Moore LB, Xue Y, Peng L, Collins JL, Wisely GB, Lambert MH, Kliewer SA, Redinbo MR. Chrencik JE, et al. Among authors: kliewer sa. Mol Endocrinol. 2005 May;19(5):1125-34. doi: 10.1210/me.2004-0346. Epub 2005 Feb 10. Mol Endocrinol. 2005. PMID: 15705662

7

Identification of a novel human constitutive androstane receptor (CAR) agonist and its use in the identification of CAR target genes.

Maglich JM, Parks DJ, Moore LB, Collins JL, Goodwin B, Billin AN, Stoltz CA, Kliewer SA, Lambert MH, Willson TM, Moore JT. Maglich JM, et al. Among authors: kliewer sa. J Biol Chem. 2003 May 9;278(19):17277-83. doi: 10.1074/jbc.M300138200. Epub 2003 Feb 27. J Biol Chem. 2003. PMID: 12611900

8

International Union of Pharmacology. LXII. The NR1H and NR1I receptors: constitutive androstane receptor, pregnene X receptor, farnesoid X receptor alpha, farnesoid X receptor beta, liver X receptor alpha, liver X receptor beta, and vitamin D receptor.

Moore DD, Kato S, Xie W, Mangelsdorf DJ, Schmidt DR, Xiao R, Kliewer SA. Moore DD, et al. Among authors: kliewer sa. Pharmacol Rev. 2006 Dec;58(4):742-59. doi: 10.1124/pr.58.4.6. Pharmacol Rev. 2006. PMID: 17132852 Review.

9

2.1 A crystal structure of human PXR in complex with the St. John's wort compound hyperforin.

Watkins RE, Maglich JM, Moore LB, Wisely GB, Noble SM, Davis-Searles PR, Lambert MH, Kliewer SA, Redinbo MR. Watkins RE, et al. Among authors: kliewer sa. Biochemistry. 2003 Feb 18;42(6):1430-8. doi: 10.1021/bi0268753. Biochemistry. 2003. PMID: 12578355

10

Nuclear receptors. I. Nuclear receptors and bile acid homeostasis.

Goodwin B, Kliewer SA. Goodwin B, et al. Among authors: kliewer sa. Am J Physiol Gastrointest Liver Physiol. 2002 Jun;282(6):G926-31. doi: 10.1152/ajpgi.00044.2002. Am J Physiol Gastrointest Liver Physiol. 2002. PMID: 12016116 Review.

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