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Heart rate adjustment of exercise-induced ST segment depression. Improved risk stratification in the Framingham Offspring Study
Okin PM, et al. Circulation 1991. Among authors: Kligfield P. PMID 1999037
When a Cox proportional hazards model with adjustment for age and sex was used, a positive exercise electrocardiogram by standard criteria (greater than or equal to 0.1 mV horizontal or downsloping ST segment depression) was not predictive of new CHD events (chi 2 = 0.40, p = 0.52). ...After multivariate adjustment for age, sex, smoking, total cholesterol level, fasting glucose level, diastolic blood pressure, and electrocardiographic evidence of left ventricular hypertrophy, the combined delta ST/HR index and rate-recovery loop criteria remained predictive of coronary events (chi 2 = 5.45, p = 0.02). ...
When a Cox proportional hazards model with adjustment for age and sex was used, a positive exercise electrocardiogram by standard criteria ( …
Mitral regurgitation: relationship of noninvasive descriptors of right and left ventricular performance to clinical and hemodynamic findings and to prognosis in medically and surgically treated patients
Hochreiter C, et al. Circulation 1986. Among authors: Kligfield P. PMID 3698235
At entry, symptom status correlated best with radionuclide-based right ventricular ejection fraction (RVEF) and left atrial size, while treadmill exercise tolerance correlated best with RVEF during exercise (r = .48, p less than .005). ...On the 24 hr ambulatory electrocardiogram, nonsustained ventricular tachycardia was present in 29% of patients, most frequently when both RVEF and left ventricular ejection fraction (LVEF) were subnormal (p = .03 vs other patients). ...
At entry, symptom status correlated best with radionuclide-based right ventricular ejection fraction (RVEF) and left atrial size, while trea …
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