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Loss of mitochondrial peptidase Clpp leads to infertility, hearing loss plus growth retardation via accumulation of CLPX, mtDNA and inflammatory factors.
Gispert S, Parganlija D, Klinkenberg M, Dröse S, Wittig I, Mittelbronn M, Grzmil P, Koob S, Hamann A, Walter M, Büchel F, Adler T, Hrabé de Angelis M, Busch DH, Zell A, Reichert AS, Brandt U, Osiewacz HD, Jendrach M, Auburger G. Gispert S, et al. Among authors: klinkenberg m. Hum Mol Genet. 2013 Dec 15;22(24):4871-87. doi: 10.1093/hmg/ddt338. Epub 2013 Jul 12. Hum Mol Genet. 2013. PMID: 23851121 Free PMC article.
Loss of PINK1 impairs stress-induced autophagy and cell survival.
Parganlija D, Klinkenberg M, Domínguez-Bautista J, Hetzel M, Gispert S, Chimi MA, Dröse S, Mai S, Brandt U, Auburger G, Jendrach M. Parganlija D, et al. Among authors: klinkenberg m. PLoS One. 2014 Apr 21;9(4):e95288. doi: 10.1371/journal.pone.0095288. eCollection 2014. PLoS One. 2014. PMID: 24751806 Free PMC article.
Primary skin fibroblasts as a model of Parkinson's disease.
Auburger G, Klinkenberg M, Drost J, Marcus K, Morales-Gordo B, Kunz WS, Brandt U, Broccoli V, Reichmann H, Gispert S, Jendrach M. Auburger G, et al. Among authors: klinkenberg m. Mol Neurobiol. 2012 Aug;46(1):20-7. doi: 10.1007/s12035-012-8245-1. Epub 2012 Feb 19. Mol Neurobiol. 2012. PMID: 22350618 Free PMC article. Review.
Parkinson patient fibroblasts show increased alpha-synuclein expression.
Hoepken HH, Gispert S, Azizov M, Klinkenberg M, Ricciardi F, Kurz A, Morales-Gordo B, Bonin M, Riess O, Gasser T, Kögel D, Steinmetz H, Auburger G. Hoepken HH, et al. Among authors: klinkenberg m. Exp Neurol. 2008 Aug;212(2):307-13. doi: 10.1016/j.expneurol.2008.04.004. Epub 2008 Apr 16. Exp Neurol. 2008. PMID: 18511044
59 results