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Protein promiscuity: drug resistance and native functions--HIV-1 case.
Fernández A, Tawfik DS, Berkhout B, Sanders R, Kloczkowski A, Sen T, Jernigan B. Fernández A, et al. Among authors: kloczkowski a. J Biomol Struct Dyn. 2005 Jun;22(6):615-24. doi: 10.1080/07391102.2005.10531228. J Biomol Struct Dyn. 2005. PMID: 15842167
The association of a drug with its target protein has the effect of blocking the protein activity and is termed a promiscuous function to distinguish from the protein's native function (Tawfik and associates, Nat. ...Disordered proteins represent a more extre …
The association of a drug with its target protein has the effect of blocking the protein activity and is termed a promiscuous …
A DNA-centric look at protein-DNA complexes.
Sen TZ, Kloczkowski A, Jernigan RL. Sen TZ, et al. Among authors: kloczkowski a. Structure. 2006 Sep;14(9):1341-2. doi: 10.1016/j.str.2006.08.003. Structure. 2006. PMID: 16962964 Free article.
GOR V server for protein secondary structure prediction.
Sen TZ, Jernigan RL, Garnier J, Kloczkowski A. Sen TZ, et al. Among authors: kloczkowski a. Bioinformatics. 2005 Jun 1;21(11):2787-8. doi: 10.1093/bioinformatics/bti408. Epub 2005 Mar 29. Bioinformatics. 2005. PMID: 15797907 Free PMC article.
Prediction of protein secondary structure by mining structural fragment database.
Cheng H, Sen TZ, Kloczkowski A, Margaritis D, Jernigan RL. Cheng H, et al. Among authors: kloczkowski a. Polymer (Guildf). 2005 May 26;46(12):4314-4321. doi: 10.1016/j.polymer.2005.02.040. Polymer (Guildf). 2005. PMID: 19081746 Free PMC article.
A new method for predicting protein secondary structure from amino acid sequence has been developed. ...Preliminary data show that combining the fragment mining approach with GOR V (Kloczkowski et al, Proteins 49 (2002) 154-166) for regions of low sequence similarit
A new method for predicting protein secondary structure from amino acid sequence has been developed. ...Preliminary data show that co
111 results