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CpG islands recruit a histone H3 lysine 36 demethylase.
Blackledge NP, Zhou JC, Tolstorukov MY, Farcas AM, Park PJ, Klose RJ. Blackledge NP, et al. Among authors: klose rj. Mol Cell. 2010 Apr 23;38(2):179-90. doi: 10.1016/j.molcel.2010.04.009. Mol Cell. 2010. PMID: 20417597 Free PMC article.
CpG island chromatin: a platform for gene regulation.
Blackledge NP, Klose R. Blackledge NP, et al. Epigenetics. 2011 Feb;6(2):147-52. doi: 10.4161/epi.6.2.13640. Epub 2011 Feb 1. Epigenetics. 2011. PMID: 20935486 Free PMC article.
The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases.
Chowdhury R, Yeoh KK, Tian YM, Hillringhaus L, Bagg EA, Rose NR, Leung IK, Li XS, Woon EC, Yang M, McDonough MA, King ON, Clifton IJ, Klose RJ, Claridge TD, Ratcliffe PJ, Schofield CJ, Kawamura A. Chowdhury R, et al. Among authors: klose rj. EMBO Rep. 2011 May;12(5):463-9. doi: 10.1038/embor.2011.43. Epub 2011 Apr 1. EMBO Rep. 2011. PMID: 21460794 Free PMC article.
Plant growth regulator daminozide is a selective inhibitor of human KDM2/7 histone demethylases.
Rose NR, Woon EC, Tumber A, Walport LJ, Chowdhury R, Li XS, King ON, Lejeune C, Ng SS, Krojer T, Chan MC, Rydzik AM, Hopkinson RJ, Che KH, Daniel M, Strain-Damerell C, Gileadi C, Kochan G, Leung IK, Dunford J, Yeoh KK, Ratcliffe PJ, Burgess-Brown N, von Delft F, Muller S, Marsden B, Brennan PE, McDonough MA, Oppermann U, Klose RJ, Schofield CJ, Kawamura A. Rose NR, et al. Among authors: klose rj. J Med Chem. 2012 Jul 26;55(14):6639-43. doi: 10.1021/jm300677j. Epub 2012 Jul 11. J Med Chem. 2012. PMID: 22724510 Free PMC article.
73 results