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Serial deletions and duplications suggest a mechanism for the collinearity of Hoxd genes in limbs.
Kmita M, Fraudeau N, Hérault Y, Duboule D. Kmita M, et al. Nature. 2002 Nov 14;420(6912):145-50. doi: 10.1038/nature01189. Nature. 2002. PMID: 12432383
Mechanisms of Hox gene colinearity: transposition of the anterior Hoxb1 gene into the posterior HoxD complex.
Kmita M, van Der Hoeven F, Zákány J, Krumlauf R, Duboule D. Kmita M, et al. Genes Dev. 2000 Jan 15;14(2):198-211. Genes Dev. 2000. PMID: 10652274 Free PMC article.
Targeted inversion of a polar silencer within the HoxD complex re-allocates domains of enhancer sharing.
Kmita M, Kondo T, Duboule D. Kmita M, et al. Nat Genet. 2000 Dec;26(4):451-4. doi: 10.1038/82593. Nat Genet. 2000. PMID: 11101844
Localized and transient transcription of Hox genes suggests a link between patterning and the segmentation clock.
Zákány J, Kmita M, Alarcon P, de la Pompa JL, Duboule D. Zákány J, et al. Among authors: kmita m. Cell. 2001 Jul 27;106(2):207-17. doi: 10.1016/s0092-8674(01)00436-6. Cell. 2001. PMID: 11511348
A nested deletion approach to generate Cre deleter mice with progressive Hox profiles.
Hérault Y, Kmita M, Sawaya CC, Duboule D. Hérault Y, et al. Among authors: kmita m. Int J Dev Biol. 2002 Jan;46(1):185-91. Int J Dev Biol. 2002. PMID: 11902682
Evolutionary conserved sequences are required for the insulation of the vertebrate Hoxd complex in neural cells.
Kmita M, Tarchini B, Duboule D, Hérault Y. Kmita M, et al. Development. 2002 Dec;129(23):5521-8. doi: 10.1242/dev.00151. Development. 2002. PMID: 12403721
Organizing axes in time and space; 25 years of colinear tinkering.
Kmita M, Duboule D. Kmita M, et al. Science. 2003 Jul 18;301(5631):331-3. doi: 10.1126/science.1085753. Science. 2003. PMID: 12869751 Review.
A dual role for Hox genes in limb anterior-posterior asymmetry.
Zákány J, Kmita M, Duboule D. Zákány J, et al. Among authors: kmita m. Science. 2004 Jun 11;304(5677):1669-72. doi: 10.1126/science.1096049. Science. 2004. PMID: 15192229
Early developmental arrest of mammalian limbs lacking HoxA/HoxD gene function.
Kmita M, Tarchini B, Zàkàny J, Logan M, Tabin CJ, Duboule D. Kmita M, et al. Nature. 2005 Jun 23;435(7045):1113-6. doi: 10.1038/nature03648. Nature. 2005. PMID: 15973411
Regulatory constraints in the evolution of the tetrapod limb anterior-posterior polarity.
Tarchini B, Duboule D, Kmita M. Tarchini B, et al. Among authors: kmita m. Nature. 2006 Oct 26;443(7114):985-8. doi: 10.1038/nature05247. Nature. 2006. PMID: 17066034
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