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Dynein structure and power stroke.
Burgess SA, Walker ML, Sakakibara H, Knight PJ, Oiwa K. Burgess SA, et al. Among authors: knight pj. Nature. 2003 Feb 13;421(6924):715-8. doi: 10.1038/nature01377. Nature. 2003. PMID: 12610617
A1603P and K1617del, Mutations in β-Cardiac Myosin Heavy Chain that Cause Laing Early-Onset Distal Myopathy, Affect Secondary Structure and Filament Formation In Vitro and In Vivo.
Parker F, Batchelor M, Wolny M, Hughes R, Knight PJ, Peckham M. Parker F, et al. Among authors: knight pj. J Mol Biol. 2018 May 11;430(10):1459-1478. doi: 10.1016/j.jmb.2018.04.006. Epub 2018 Apr 14. J Mol Biol. 2018. PMID: 29660325 Free PMC article.
The Inner Centromere Protein (INCENP) Coil Is a Single α-Helix (SAH) Domain That Binds Directly to Microtubules and Is Important for Chromosome Passenger Complex (CPC) Localization and Function in Mitosis.
Samejima K, Platani M, Wolny M, Ogawa H, Vargiu G, Knight PJ, Peckham M, Earnshaw WC. Samejima K, et al. Among authors: knight pj. J Biol Chem. 2015 Aug 28;290(35):21460-72. doi: 10.1074/jbc.M115.645317. Epub 2015 Jul 14. J Biol Chem. 2015. PMID: 26175154 Free PMC article.
Stable single α-helices are constant force springs in proteins.
Wolny M, Batchelor M, Knight PJ, Paci E, Dougan L, Peckham M. Wolny M, et al. Among authors: knight pj. J Biol Chem. 2014 Oct 3;289(40):27825-35. doi: 10.1074/jbc.M114.585679. Epub 2014 Aug 13. J Biol Chem. 2014. PMID: 25122759 Free PMC article.
Flexibility within the heads of muscle myosin-2 molecules.
Billington N, Revill DJ, Burgess SA, Chantler PD, Knight PJ. Billington N, et al. Among authors: knight pj. J Mol Biol. 2014 Feb 20;426(4):894-907. doi: 10.1016/j.jmb.2013.11.028. Epub 2013 Dec 9. J Mol Biol. 2014. PMID: 24333017 Free PMC article.
Is the dynein motor a winch?
Burgess SA, Knight PJ. Burgess SA, et al. Among authors: knight pj. Curr Opin Struct Biol. 2004 Apr;14(2):138-46. doi: 10.1016/ Curr Opin Struct Biol. 2004. PMID: 15093827 Review.
Functions and mechanics of dynein motor proteins.
Roberts AJ, Kon T, Knight PJ, Sutoh K, Burgess SA. Roberts AJ, et al. Among authors: knight pj. Nat Rev Mol Cell Biol. 2013 Nov;14(11):713-26. doi: 10.1038/nrm3667. Epub 2013 Sep 25. Nat Rev Mol Cell Biol. 2013. PMID: 24064538 Free PMC article. Review.
Direct observation shows superposition and large scale flexibility within cytoplasmic dynein motors moving along microtubules.
Imai H, Shima T, Sutoh K, Walker ML, Knight PJ, Kon T, Burgess SA. Imai H, et al. Among authors: knight pj. Nat Commun. 2015 Sep 14;6:8179. doi: 10.1038/ncomms9179. Nat Commun. 2015. PMID: 26365535 Free PMC article.
ATP-driven remodeling of the linker domain in the dynein motor.
Roberts AJ, Malkova B, Walker ML, Sakakibara H, Numata N, Kon T, Ohkura R, Edwards TA, Knight PJ, Sutoh K, Oiwa K, Burgess SA. Roberts AJ, et al. Among authors: knight pj. Structure. 2012 Oct 10;20(10):1670-80. doi: 10.1016/j.str.2012.07.003. Epub 2012 Aug 2. Structure. 2012. PMID: 22863569 Free PMC article.
Helix sliding in the stalk coiled coil of dynein couples ATPase and microtubule binding.
Kon T, Imamula K, Roberts AJ, Ohkura R, Knight PJ, Gibbons IR, Burgess SA, Sutoh K. Kon T, et al. Among authors: knight pj. Nat Struct Mol Biol. 2009 Mar;16(3):325-33. doi: 10.1038/nsmb.1555. Epub 2009 Feb 8. Nat Struct Mol Biol. 2009. PMID: 19198589 Free PMC article.
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