Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Text availability
Article attribute
Article type
Publication date

Search Results

33 results
Filters applied: . Clear all Results are displayed in a computed author sort order. Results by year timeline is unavailable
Page 1
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy.
Farmer H, McCabe N, Lord CJ, Tutt AN, Johnson DA, Richardson TB, Santarosa M, Dillon KJ, Hickson I, Knights C, Martin NM, Jackson SP, Smith GC, Ashworth A. Farmer H, et al. Among authors: knights c. Nature. 2005 Apr 14;434(7035):917-21. doi: 10.1038/nature03445. Nature. 2005. PMID: 15829967
4-[3-(4-cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorobenzyl]-2H-phthalazin-1-one: a novel bioavailable inhibitor of poly(ADP-ribose) polymerase-1.
Menear KA, Adcock C, Boulter R, Cockcroft XL, Copsey L, Cranston A, Dillon KJ, Drzewiecki J, Garman S, Gomez S, Javaid H, Kerrigan F, Knights C, Lau A, Loh VM Jr, Matthews IT, Moore S, O'Connor MJ, Smith GC, Martin NM. Menear KA, et al. Among authors: knights c. J Med Chem. 2008 Oct 23;51(20):6581-91. doi: 10.1021/jm8001263. Epub 2008 Sep 19. J Med Chem. 2008. PMID: 18800822
The PARP Inhibitor AZD2461 Provides Insights into the Role of PARP3 Inhibition for Both Synthetic Lethality and Tolerability with Chemotherapy in Preclinical Models.
Oplustil O'Connor L, Rulten SL, Cranston AN, Odedra R, Brown H, Jaspers JE, Jones L, Knights C, Evers B, Ting A, Bradbury RH, Pajic M, Rottenberg S, Jonkers J, Rudge D, Martin NM, Caldecott KW, Lau A, O'Connor MJ. Oplustil O'Connor L, et al. Among authors: knights c. Cancer Res. 2016 Oct 15;76(20):6084-6094. doi: 10.1158/0008-5472.CAN-15-3240. Epub 2016 Aug 22. Cancer Res. 2016. PMID: 27550455 Free article.
DNA-dependent protein kinase (DNA-PK) inhibitors. Synthesis and biological activity of quinolin-4-one and pyridopyrimidin-4-one surrogates for the chromen-4-one chemotype.
Cano C, Barbeau OR, Bailey C, Cockcroft XL, Curtin NJ, Duggan H, Frigerio M, Golding BT, Hardcastle IR, Hummersone MG, Knights C, Menear KA, Newell DR, Richardson CJ, Smith GC, Spittle B, Griffin RJ. Cano C, et al. Among authors: knights c. J Med Chem. 2010 Dec 23;53(24):8498-507. doi: 10.1021/jm100608j. Epub 2010 Nov 16. J Med Chem. 2010. PMID: 21080722
. ; Richardson , C. ; Rigoreau , L. ; Smith , G. C. M. Bioorg. Med. Chem. Lett. 2004 , 14 , 6083 - 6087) as a potent inhibitor (IC₅₀ = 30 nM) of DNA-dependent protein kinase (DNA-PK), we have investigated analogues in which the chromen-4-one core template has been r …
. ; Richardson , C. ; Rigoreau , L. ; Smith , G. C. M. Bioorg. Med. Chem. Lett. 2004 , 14 , 6083 - 6087) as a potent inhibitor …
Quantitative Chemical Proteomic Profiling of Ubiquitin Specific Proteases in Intact Cancer Cells.
Ward JA, McLellan L, Stockley M, Gibson KR, Whitlock GA, Knights C, Harrigan JA, Jacq X, Tate EW. Ward JA, et al. Among authors: knights c. ACS Chem Biol. 2016 Dec 16;11(12):3268-3272. doi: 10.1021/acschembio.6b00766. Epub 2016 Oct 31. ACS Chem Biol. 2016. PMID: 27779380 Free article.
Managing out of hours clinical photography at the University Hospitals Bristol.
Brinkworth S, Kenny A, Knights C. Brinkworth S, et al. Among authors: knights c. J Vis Commun Med. 2018 Apr;41(2):85-89. doi: 10.1080/17453054.2018.1441708. Epub 2018 Mar 25. J Vis Commun Med. 2018. PMID: 29577774
PicSafe Medi: a clinical photography app review.
Lo MC, Brinkworth S, Knights C, Mackie I. Lo MC, et al. Among authors: knights c. J Vis Commun Med. 2015;38(3-4):241-3. doi: 10.3109/17453054.2015.1108296. J Vis Commun Med. 2015. PMID: 26828558
Figure 1: An App Review.
Knights C, Shah V. Knights C, et al. J Vis Commun Med. 2015;38(3-4):236-40. doi: 10.3109/17453054.2015.1108292. J Vis Commun Med. 2015. PMID: 26828557 No abstract available.
Nociceptive Sensitizers Are Regulated in Damaged Joint Tissues, Including Articular Cartilage, When Osteoarthritic Mice Display Pain Behavior.
Driscoll C, Chanalaris A, Knights C, Ismail H, Sacitharan PK, Gentry C, Bevan S, Vincent TL. Driscoll C, et al. Among authors: knights c. Arthritis Rheumatol. 2016 Apr;68(4):857-67. doi: 10.1002/art.39523. Arthritis Rheumatol. 2016. PMID: 26605536 Free PMC article.
The evaluation of pain in amyotrophic lateral sclerosis: a case controlled observational study.
Wallace VC, Ellis CM, Burman R, Knights C, Shaw CE, Al-Chalabi A. Wallace VC, et al. Among authors: knights c. Amyotroph Lateral Scler Frontotemporal Degener. 2014 Dec;15(7-8):520-7. doi: 10.3109/21678421.2014.951944. Epub 2014 Sep 10. Amyotroph Lateral Scler Frontotemporal Degener. 2014. PMID: 25204842
33 results
Jump to page
Feedback