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Lipid mediators of insulin resistance.
Holland WL, Knotts TA, Chavez JA, Wang LP, Hoehn KL, Summers SA. Holland WL, et al. Among authors: knotts ta. Nutr Rev. 2007 Jun;65(6 Pt 2):S39-46. doi: 10.1111/j.1753-4887.2007.tb00327.x. Nutr Rev. 2007. PMID: 17605313 Review.
Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice.
Holland WL, Bikman BT, Wang LP, Yuguang G, Sargent KM, Bulchand S, Knotts TA, Shui G, Clegg DJ, Wenk MR, Pagliassotti MJ, Scherer PE, Summers SA. Holland WL, et al. Among authors: knotts ta. J Clin Invest. 2011 May;121(5):1858-70. doi: 10.1172/JCI43378. Epub 2011 Apr 1. J Clin Invest. 2011. PMID: 21490391 Free PMC article.
Increased P85alpha is a potent negative regulator of skeletal muscle insulin signaling and induces in vivo insulin resistance associated with growth hormone excess.
Barbour LA, Mizanoor Rahman S, Gurevich I, Leitner JW, Fischer SJ, Roper MD, Knotts TA, Vo Y, McCurdy CE, Yakar S, Leroith D, Kahn CR, Cantley LC, Friedman JE, Draznin B. Barbour LA, et al. Among authors: knotts ta. J Biol Chem. 2005 Nov 11;280(45):37489-94. doi: 10.1074/jbc.M506967200. Epub 2005 Sep 8. J Biol Chem. 2005. PMID: 16166093 Free article.
Increased phosphoenolpyruvate carboxykinase gene expression and steatosis during hepatitis C virus subgenome replication: role of nonstructural component 5A and CCAAT/enhancer-binding protein β.
Qadri I, Choudhury M, Rahman SM, Knotts TA, Janssen RC, Schaack J, Iwahashi M, Puljak L, Simon FR, Kilic G, Fitz JG, Friedman JE. Qadri I, et al. Among authors: knotts ta. J Biol Chem. 2012 Oct 26;287(44):37340-51. doi: 10.1074/jbc.M112.384743. Epub 2012 Sep 6. J Biol Chem. 2012. PMID: 22955269 Free PMC article.
61 results