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Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin.
Knowler WC, Barrett-Connor E, Fowler SE, Hamman RF, Lachin JM, Walker EA, Nathan DM; Diabetes Prevention Program Research Group. Knowler WC, et al. N Engl J Med. 2002 Feb 7;346(6):393-403. doi: 10.1056/NEJMoa012512. N Engl J Med. 2002. PMID: 11832527 Free PMC article. Clinical Trial.
The long-term effectiveness of a lifestyle intervention in severely obese individuals.
Unick JL, Beavers D, Bond DS, Clark JM, Jakicic JM, Kitabchi AE, Knowler WC, Wadden TA, Wagenknecht LE, Wing RR; Look AHEAD Research Group. Unick JL, et al. Among authors: knowler wc. Am J Med. 2013 Mar;126(3):236-42, 242.e1-2. doi: 10.1016/j.amjmed.2012.10.010. Am J Med. 2013. PMID: 23410564 Free PMC article. Clinical Trial.
Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes.
Look AHEAD Research Group, Wing RR, Bolin P, Brancati FL, Bray GA, Clark JM, Coday M, Crow RS, Curtis JM, Egan CM, Espeland MA, Evans M, Foreyt JP, Ghazarian S, Gregg EW, Harrison B, Hazuda HP, Hill JO, Horton ES, Hubbard VS, Jakicic JM, Jeffery RW, Johnson KC, Kahn SE, Kitabchi AE, Knowler WC, Lewis CE, Maschak-Carey BJ, Montez MG, Murillo A, Nathan DM, Patricio J, Peters A, Pi-Sunyer X, Pownall H, Reboussin D, Regensteiner JG, Rickman AD, Ryan DH, Safford M, Wadden TA, Wagenknecht LE, West DS, Williamson DF, Yanovski SZ. Look AHEAD Research Group, et al. Among authors: knowler wc. N Engl J Med. 2013 Jul 11;369(2):145-54. doi: 10.1056/NEJMoa1212914. Epub 2013 Jun 24. N Engl J Med. 2013. PMID: 23796131 Free PMC article. Clinical Trial.
Long-Term Weight Loss With Metformin or Lifestyle Intervention in the Diabetes Prevention Program Outcomes Study.
Apolzan JW, Venditti EM, Edelstein SL, Knowler WC, Dabelea D, Boyko EJ, Pi-Sunyer X, Kalyani RR, Franks PW, Srikanthan P, Gadde KM; Diabetes Prevention Program Research Group. Apolzan JW, et al. Among authors: knowler wc. Ann Intern Med. 2019 May 21;170(10):682-690. doi: 10.7326/M18-1605. Epub 2019 Apr 23. Ann Intern Med. 2019. PMID: 31009939 Free PMC article. Clinical Trial.
Effect of a long-term intensive lifestyle intervention on prevalence of cognitive impairment.
Espeland MA, Luchsinger JA, Baker LD, Neiberg R, Kahn SE, Arnold SE, Wing RR, Blackburn GL, Bray G, Evans M, Hazuda HP, Jeffery RW, Wilson VM, Clark JM, Coday M, Demos-McDermott K, Foreyt JP, Greenway F, Hill JO, Horton ES, Jakicic JM, Johnson KC, Knowler WC, Lewis CE, Nathan DM, Peters A, Pi-Sunyer X, Pownall H, Wadden TA, Rapp SR; Look AHEAD Study Group. Espeland MA, et al. Among authors: knowler wc. Neurology. 2017 May 23;88(21):2026-2035. doi: 10.1212/WNL.0000000000003955. Epub 2017 Apr 26. Neurology. 2017. PMID: 28446656 Free PMC article. Clinical Trial.
The Effect of Intentional Weight Loss on Fracture Risk in Persons With Diabetes: Results From the Look AHEAD Randomized Clinical Trial.
Johnson KC, Bray GA, Cheskin LJ, Clark JM, Egan CM, Foreyt JP, Garcia KR, Glasser S, Greenway FL, Gregg EW, Hazuda HP, Hergenroeder A, Hill JO, Horton ES, Jakicic JM, Jeffery RW, Kahn SE, Knowler WC, Lewis CE, Miller M, Montez MG, Nathan DM, Patricio JL, Peters AL, Pi-Sunyer X, Pownall HJ, Reboussin D, Redmon JB, Steinberg H, Wadden TA, Wagenknecht LE, Wing RR, Womack CR, Yanovski SZ, Zhang P, Schwartz AV; Look AHEAD Study Group. Johnson KC, et al. Among authors: knowler wc. J Bone Miner Res. 2017 Nov;32(11):2278-2287. doi: 10.1002/jbmr.3214. Epub 2017 Jul 28. J Bone Miner Res. 2017. PMID: 28678345 Free PMC article. Clinical Trial.
Impact of intensive lifestyle intervention on preference-based quality of life in type 2 diabetes: Results from the Look AHEAD trial.
Zhang P, Hire D, Espeland MA, Knowler WC, Thomas S, Tsai AG, Glick HA; Look AHEAD Research Group. Zhang P, et al. Among authors: knowler wc. Obesity (Silver Spring). 2016 Apr;24(4):856-64. doi: 10.1002/oby.21445. Epub 2016 Mar 8. Obesity (Silver Spring). 2016. PMID: 27028282 Free PMC article. Clinical Trial.
Lifestyle intervention improves heart rate recovery from exercise in adults with type 2 diabetes: results from the Look AHEAD study.
Ribisl PM, Gaussoin SA, Lang W, Bahnson J, Connelly SA, Horton ES, Jakicic JM, Killean T, Kitzman DW, Knowler WC, Stewart KJ; Look AHEAD Research Group. Ribisl PM, et al. Among authors: knowler wc. J Obes. 2012;2012:309196. doi: 10.1155/2012/309196. Epub 2012 Nov 22. J Obes. 2012. PMID: 23227314 Free PMC article.
Metformin for diabetes prevention: insights gained from the Diabetes Prevention Program/Diabetes Prevention Program Outcomes Study.
Aroda VR, Knowler WC, Crandall JP, Perreault L, Edelstein SL, Jeffries SL, Molitch ME, Pi-Sunyer X, Darwin C, Heckman-Stoddard BM, Temprosa M, Kahn SE, Nathan DM; Diabetes Prevention Program Research Group. Aroda VR, et al. Among authors: knowler wc. Diabetologia. 2017 Sep;60(9):1601-1611. doi: 10.1007/s00125-017-4361-9. Epub 2017 Aug 2. Diabetologia. 2017. PMID: 28770322 Free PMC article. Review.
Variation in Maturity-Onset Diabetes of the Young Genes Influence Response to Interventions for Diabetes Prevention.
Billings LK, Jablonski KA, Warner AS, Cheng YC, McAteer JB, Tipton L, Shuldiner AR, Ehrmann DA, Manning AK, Dabelea D, Franks PW, Kahn SE, Pollin TI, Knowler WC, Altshuler D, Florez JC; Diabetes Prevention Program Research Group. Billings LK, et al. Among authors: knowler wc. J Clin Endocrinol Metab. 2017 Aug 1;102(8):2678-2689. doi: 10.1210/jc.2016-3429. J Clin Endocrinol Metab. 2017. PMID: 28453780 Free PMC article. Clinical Trial.
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