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Bax suppresses tumorigenesis and stimulates apoptosis in vivo.
Yin C, Knudson CM, Korsmeyer SJ, Van Dyke T. Yin C, et al. Among authors: knudson cm. Nature. 1997 Feb 13;385(6617):637-40. doi: 10.1038/385637a0. Nature. 1997. PMID: 9024662
Lymphoma development in Bax transgenic mice is inhibited by Bcl-2 and associated with chromosomal instability.
Luke JJ, Van De Wetering CI, Knudson CM. Luke JJ, et al. Among authors: knudson cm. Cell Death Differ. 2003 Jun;10(6):740-8. doi: 10.1038/sj.cdd.4401233. Cell Death Differ. 2003. PMID: 12761582
Complete dissociation of motor neuron death from motor dysfunction by Bax deletion in a mouse model of ALS.
Gould TW, Buss RR, Vinsant S, Prevette D, Sun W, Knudson CM, Milligan CE, Oppenheim RW. Gould TW, et al. Among authors: knudson cm. J Neurosci. 2006 Aug 23;26(34):8774-86. doi: 10.1523/JNEUROSCI.2315-06.2006. J Neurosci. 2006. PMID: 16928866 Free PMC article.
Bax-dependent spermatogonia apoptosis is required for testicular development and spermatogenesis.
Russell LD, Chiarini-Garcia H, Korsmeyer SJ, Knudson CM. Russell LD, et al. Among authors: knudson cm. Biol Reprod. 2002 Apr;66(4):950-8. doi: 10.1095/biolreprod66.4.950. Biol Reprod. 2002. PMID: 11906913
The pro-apoptotic gene Bax is required for the death of ectopic primordial germ cells during their migration in the mouse embryo.
Stallock J, Molyneaux K, Schaible K, Knudson CM, Wylie C. Stallock J, et al. Among authors: knudson cm. Development. 2003 Dec;130(26):6589-97. doi: 10.1242/dev.00898. Development. 2003. PMID: 14660547
Low-dose radiation-induced enhancement of thymic lymphomagenesis in Lck-Bax mice is dependent on LET and gender.
Jacobus JA, Duda CG, Coleman MC, Martin SM, Mapuskar K, Mao G, Smith BJ, Aykin-Burns N, Guida P, Gius D, Domann FE, Knudson CM, Spitz DR. Jacobus JA, et al. Among authors: knudson cm. Radiat Res. 2013 Aug;180(2):156-65. doi: 10.1667/RR3293.1. Epub 2013 Jul 2. Radiat Res. 2013. PMID: 23819597 Free PMC article.
Obesity-associated NLRC4 inflammasome activation drives breast cancer progression.
Kolb R, Phan L, Borcherding N, Liu Y, Yuan F, Janowski AM, Xie Q, Markan KR, Li W, Potthoff MJ, Fuentes-Mattei E, Ellies LG, Knudson CM, Lee MH, Yeung SJ, Cassel SL, Sutterwala FS, Zhang W. Kolb R, et al. Among authors: knudson cm. Nat Commun. 2016 Oct 6;7:13007. doi: 10.1038/ncomms13007. Nat Commun. 2016. PMID: 27708283 Free PMC article.
BCLW mediates survival of postmitotic Sertoli cells by regulating BAX activity.
Ross AJ, Amy SP, Mahar PL, Lindsten T, Knudson CM, Thompson CB, Korsmeyer SJ, MacGregor GR. Ross AJ, et al. Among authors: knudson cm. Dev Biol. 2001 Nov 15;239(2):295-308. doi: 10.1006/dbio.2001.0445. Dev Biol. 2001. PMID: 11784036
BAX contributes to apoptotic-like death following neonatal hypoxia-ischemia: evidence for distinct apoptosis pathways.
Gibson ME, Han BH, Choi J, Knudson CM, Korsmeyer SJ, Parsadanian M, Holtzman DM. Gibson ME, et al. Among authors: knudson cm. Mol Med. 2001 Sep;7(9):644-55. Mol Med. 2001. PMID: 11778654 Free PMC article.
Prolongation of ovarian lifespan into advanced chronological age by Bax-deficiency.
Perez GI, Robles R, Knudson CM, Flaws JA, Korsmeyer SJ, Tilly JL. Perez GI, et al. Among authors: knudson cm. Nat Genet. 1999 Feb;21(2):200-3. doi: 10.1038/5985. Nat Genet. 1999. PMID: 9988273
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