Knutson TP - Search Results

1

Combining nilotinib and PD-L1 blockade reverses CD4+ T-cell dysfunction and prevents relapse in acute B-cell leukemia.

Tracy SI, Venkatesh H, Hekim C, Heltemes-Harris LM, Knutson TP, Bachanova V, Farrar MA. Tracy SI, et al. Among authors: knutson tp. Blood. 2022 Jul 28;140(4):335-348. doi: 10.1182/blood.2021015341. Blood. 2022. PMID: 35275990 Free PMC article.

2

JAK/STAT inhibition in macrophages promotes therapeutic resistance by inducing expression of protumorigenic factors.

Irey EA, Lassiter CM, Brady NJ, Chuntova P, Wang Y, Knutson TP, Henzler C, Chaffee TS, Vogel RI, Nelson AC, Farrar MA, Schwertfeger KL. Irey EA, et al. Among authors: knutson tp. Proc Natl Acad Sci U S A. 2019 Jun 18;116(25):12442-12451. doi: 10.1073/pnas.1816410116. Epub 2019 May 30. Proc Natl Acad Sci U S A. 2019. PMID: 31147469 Free PMC article.

3

Single-cell analysis identifies dynamic gene expression networks that govern B cell development and transformation.

Lee RD, Munro SA, Knutson TP, LaRue RS, Heltemes-Harris LM, Farrar MA. Lee RD, et al. Among authors: knutson tp. Nat Commun. 2021 Nov 25;12(1):6843. doi: 10.1038/s41467-021-27232-5. Nat Commun. 2021. PMID: 34824268 Free PMC article.

4

Nuclear corepressors NCOR1/NCOR2 regulate B cell development, maintain genomic integrity and prevent transformation.

Lee RD, Knutson TP, Munro SA, Miller JT, Heltemes-Harris LM, Mullighan CG, Jepsen K, Farrar MA. Lee RD, et al. Among authors: knutson tp. Nat Immunol. 2022 Dec;23(12):1763-1776. doi: 10.1038/s41590-022-01343-7. Epub 2022 Oct 31. Nat Immunol. 2022. PMID: 36316474 Free PMC article.

5

CD4⁺ T cells reactive to a hybrid peptide from insulin-chromogranin A adopt a distinct effector fate and are pathogenic in autoimmune diabetes.

Mitchell JS, Spanier JA, Dwyer AJ, Knutson TP, Alkhatib MH, Qian G, Weno ME, Chen Y, Shaheen ZR, Tucker CG, Kangas TO, Morales MS, Silva N, Kaisho T, Farrar MA, Fife BT. Mitchell JS, et al. Among authors: knutson tp. Immunity. 2024 Oct 8;57(10):2399-2415.e8. doi: 10.1016/j.immuni.2024.07.024. Epub 2024 Aug 29. Immunity. 2024. PMID: 39214091 Free article.

6

Leukemia escapes immunity by imposing a type 1 regulatory program on neoantigen-specific CD4+ T cells.

Venkatesh H, Granados Centeno E, Luo Q, Arroyo M, Heltemes-Harris L, Knutson TP, Qiu Y, Haaning A, Webber BR, Bachanova V, Farrar MA, Tracy SI. Venkatesh H, et al. Among authors: knutson tp. Blood. 2025 Dec 4;146(23):2779-2793. doi: 10.1182/blood.2024028194. Blood. 2025. PMID: 40906918

7

CDK11 Loss Induces Cell Cycle Dysfunction and Death of BRAF and NRAS Melanoma Cells.

Ahmed RL, Shaughnessy DP, Knutson TP, Vogel RI, Ahmed K, Kren BT, Trembley JH. Ahmed RL, et al. Among authors: knutson tp. Pharmaceuticals (Basel). 2019 Apr 2;12(2):50. doi: 10.3390/ph12020050. Pharmaceuticals (Basel). 2019. PMID: 30987032 Free PMC article.

8

CD8⁺ T cell self-tolerance permits responsiveness but limits tissue damage.

Truckenbrod EN, Burrack KS, Knutson TP, Borges da Silva H, Block KE, O'Flanagan SD, Stagliano KR, Hurwitz AA, Fulton RB, Renkema KR, Jameson SC. Truckenbrod EN, et al. Among authors: knutson tp. Elife. 2021 Apr 30;10:e65615. doi: 10.7554/eLife.65615. Elife. 2021. PMID: 33929324 Free PMC article.

9

KLRG1⁺ Memory CD8 T Cells Combine Properties of Short-Lived Effectors and Long-Lived Memory.

Renkema KR, Huggins MA, Borges da Silva H, Knutson TP, Henzler CM, Hamilton SE. Renkema KR, et al. Among authors: knutson tp. J Immunol. 2020 Aug 15;205(4):1059-1069. doi: 10.4049/jimmunol.1901512. Epub 2020 Jul 1. J Immunol. 2020. PMID: 32611727 Free PMC article.

10

Progesterone receptor-B enhances estrogen responsiveness of breast cancer cells via scaffolding PELP1- and estrogen receptor-containing transcription complexes.

Daniel AR, Gaviglio AL, Knutson TP, Ostrander JH, D'Assoro AB, Ravindranathan P, Peng Y, Raj GV, Yee D, Lange CA. Daniel AR, et al. Among authors: knutson tp. Oncogene. 2015 Jan 22;34(4):506-15. doi: 10.1038/onc.2013.579. Epub 2014 Jan 27. Oncogene. 2015. PMID: 24469035 Free PMC article.

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