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Synthesis and pharmacological evaluation of new 5-(cyclo)alkyl-5-phenyl- and 5-spiroimidazolidine-2,4-dione derivatives. Novel 5-HT1A receptor agonist with potential antidepressant and anxiolytic activity.
Czopek A, Byrtus H, Kołaczkowski M, Pawłowski M, Dybała M, Nowak G, Tatarczyńska E, Wesołowska A, Chojnacka-Wójcik E. Czopek A, et al. Among authors: kolaczkowski m. Eur J Med Chem. 2010 Apr;45(4):1295-303. doi: 10.1016/j.ejmech.2009.11.053. Epub 2009 Dec 6. Eur J Med Chem. 2010. PMID: 20060623
Antipsychotic, antidepressant, and cognitive-impairment properties of antipsychotics: rat profile and implications for behavioral and psychological symptoms of dementia.
Kołaczkowski M, Mierzejewski P, Bienkowski P, Wesołowska A, Newman-Tancredi A. Kołaczkowski M, et al. Naunyn Schmiedebergs Arch Pharmacol. 2014 Jun;387(6):545-57. doi: 10.1007/s00210-014-0966-4. Epub 2014 Mar 6. Naunyn Schmiedebergs Arch Pharmacol. 2014. PMID: 24599316 Free PMC article.
Pharmacological evaluation of the anxiolytic-like effects of EMD 386088, a partial 5-HT6 receptor agonist, in the rat elevated plus-maze and Vogel conflict tests.
Jastrzębska-Więsek M, Siwek A, Partyka A, Kubacka M, Mogilski S, Wasik A, Kołaczkowski M, Wesołowska A. Jastrzębska-Więsek M, et al. Among authors: kolaczkowski m. Neuropharmacology. 2014 Oct;85:253-62. doi: 10.1016/j.neuropharm.2014.05.036. Epub 2014 Jun 4. Neuropharmacology. 2014. PMID: 24905144
Antidepressant-like activity of EMD 386088, a 5-HT6 receptor partial agonist, following systemic acute and chronic administration to rats.
Jastrzębska-Więsek M, Siwek A, Partyka A, Szewczyk B, Sowa-Kućma M, Wasik A, Kołaczkowski M, Wesołowska A. Jastrzębska-Więsek M, et al. Among authors: kolaczkowski m. Naunyn Schmiedebergs Arch Pharmacol. 2015 Oct;388(10):1079-88. doi: 10.1007/s00210-015-1141-2. Epub 2015 Jun 16. Naunyn Schmiedebergs Arch Pharmacol. 2015. PMID: 26077660
Novel 3-(1,2,3,6-Tetrahydropyridin-4-yl)-1H-indole-Based Multifunctional Ligands with Antipsychotic-Like, Mood-Modulating, and Procognitive Activity.
Bucki A, Marcinkowska M, Śniecikowska J, Więckowski K, Pawłowski M, Głuch-Lutwin M, Gryboś A, Siwek A, Pytka K, Jastrzębska-Więsek M, Partyka A, Wesołowska A, Mierzejewski P, Kołaczkowski M. Bucki A, et al. Among authors: kolaczkowski m. J Med Chem. 2017 Sep 14;60(17):7483-7501. doi: 10.1021/acs.jmedchem.7b00839. Epub 2017 Aug 18. J Med Chem. 2017. PMID: 28763213
137 results