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Sphingosine 1-Phosphate Receptor 4 Promotes Nonalcoholic Steatohepatitis by Activating NLRP3 Inflammasome.
Hong CH, Ko MS, Kim JH, Cho H, Lee CH, Yoon JE, Yun JY, Baek IJ, Jang JE, Lee SE, Cho YK, Baek JY, Oh SJ, Lee BY, Lim JS, Lee J, Hartig SM, Conde de la Rosa L, Garcia-Ruiz C, Lee KU, Fernández-Checa JC, Choi JW, Kim S, Koh EH. Hong CH, et al. Among authors: ko ms. Cell Mol Gastroenterol Hepatol. 2022;13(3):925-947. doi: 10.1016/j.jcmgh.2021.12.002. Epub 2021 Dec 8. Cell Mol Gastroenterol Hepatol. 2022. PMID: 34890841 Free PMC article.
Protective role of endogenous plasmalogens against hepatic steatosis and steatohepatitis in mice.
Jang JE, Park HS, Yoo HJ, Baek IJ, Yoon JE, Ko MS, Kim AR, Kim HS, Park HS, Lee SE, Kim SW, Kim SJ, Leem J, Kang YM, Jung MK, Pack CG, Kim CJ, Sung CO, Lee IK, Park JY, Fernández-Checa JC, Koh EH, Lee KU. Jang JE, et al. Among authors: ko ms. Hepatology. 2017 Aug;66(2):416-431. doi: 10.1002/hep.29039. Epub 2017 Jun 29. Hepatology. 2017. PMID: 28073164 Free PMC article.
Mitophagy deficiency increases NLRP3 to induce brown fat dysfunction in mice.
Ko MS, Yun JY, Baek IJ, Jang JE, Hwang JJ, Lee SE, Heo SH, Bader DA, Lee CH, Han J, Moon JS, Lee JM, Hong EG, Lee IK, Kim SW, Park JY, Hartig SM, Kang UJ, Moore DD, Koh EH, Lee KU. Ko MS, et al. Autophagy. 2021 May;17(5):1205-1221. doi: 10.1080/15548627.2020.1753002. Epub 2020 May 13. Autophagy. 2021. PMID: 32400277 Free PMC article.
Sphingomyelin synthase 1 mediates hepatocyte pyroptosis to trigger non-alcoholic steatohepatitis.
Koh EH, Yoon JE, Ko MS, Leem J, Yun JY, Hong CH, Cho YK, Lee SE, Jang JE, Baek JY, Yoo HJ, Kim SJ, Sung CO, Lim JS, Jeong WI, Back SH, Baek IJ, Torres S, Solsona-Vilarrasa E, Conde de la Rosa L, Garcia-Ruiz C, Feldstein AE, Fernandez-Checa JC, Lee KU. Koh EH, et al. Among authors: ko ms. Gut. 2021 Oct;70(10):1954-1964. doi: 10.1136/gutjnl-2020-322509. Epub 2020 Nov 18. Gut. 2021. PMID: 33208407 Free PMC article.
325 results