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Reconstruction of the human blood-brain barrier in vitro reveals a pathogenic mechanism of APOE4 in pericytes.
Blanchard JW, Bula M, Davila-Velderrain J, Akay LA, Zhu L, Frank A, Victor MB, Bonner JM, Mathys H, Lin YT, Ko T, Bennett DA, Cam HP, Kellis M, Tsai LH. Blanchard JW, et al. Among authors: ko t. Nat Med. 2020 Jun;26(6):952-963. doi: 10.1038/s41591-020-0886-4. Epub 2020 Jun 8. Nat Med. 2020. PMID: 32514169
APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer's Disease Phenotypes in Human iPSC-Derived Brain Cell Types.
Lin YT, Seo J, Gao F, Feldman HM, Wen HL, Penney J, Cam HP, Gjoneska E, Raja WK, Cheng J, Rueda R, Kritskiy O, Abdurrob F, Peng Z, Milo B, Yu CJ, Elmsaouri S, Dey D, Ko T, Yankner BA, Tsai LH. Lin YT, et al. Neuron. 2018 Jun 27;98(6):1141-1154.e7. doi: 10.1016/j.neuron.2018.05.008. Epub 2018 May 31. Neuron. 2018. PMID: 29861287 Free PMC article.
Histone deacetylase 3 associates with MeCP2 to regulate FOXO and social behavior.
Nott A, Cheng J, Gao F, Lin YT, Gjoneska E, Ko T, Minhas P, Zamudio AV, Meng J, Zhang F, Jin P, Tsai LH. Nott A, et al. Nat Neurosci. 2016 Nov;19(11):1497-1505. doi: 10.1038/nn.4347. Epub 2016 Jul 18. Nat Neurosci. 2016. PMID: 27428650 Free PMC article.
Inhibition of p25/Cdk5 Attenuates Tauopathy in Mouse and iPSC Models of Frontotemporal Dementia.
Seo J, Kritskiy O, Watson LA, Barker SJ, Dey D, Raja WK, Lin YT, Ko T, Cho S, Penney J, Silva MC, Sheridan SD, Lucente D, Gusella JF, Dickerson BC, Haggarty SJ, Tsai LH. Seo J, et al. J Neurosci. 2017 Oct 11;37(41):9917-9924. doi: 10.1523/JNEUROSCI.0621-17.2017. Epub 2017 Sep 14. J Neurosci. 2017. PMID: 28912154 Free PMC article.
APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer's Disease Phenotypes in Human iPSC-Derived Brain Cell Types.
Lin YT, Seo J, Gao F, Feldman HM, Wen HL, Penney J, Cam HP, Gjoneska E, Raja WK, Cheng J, Rueda R, Kritskiy O, Abdurrob F, Peng Z, Milo B, Yu CJ, Elmsaouri S, Dey D, Ko T, Yankner BA, Tsai LH. Lin YT, et al. Neuron. 2018 Jun 27;98(6):1294. doi: 10.1016/j.neuron.2018.06.011. Neuron. 2018. PMID: 29953873 Free PMC article. No abstract available.
A Library of Phosphoproteomic and Chromatin Signatures for Characterizing Cellular Responses to Drug Perturbations.
Litichevskiy L, Peckner R, Abelin JG, Asiedu JK, Creech AL, Davis JF, Davison D, Dunning CM, Egertson JD, Egri S, Gould J, Ko T, Johnson SA, Lahr DL, Lam D, Liu Z, Lyons NJ, Lu X, MacLean BX, Mungenast AE, Officer A, Natoli TE, Papanastasiou M, Patel J, Sharma V, Toder C, Tubelli AA, Young JZ, Carr SA, Golub TR, Subramanian A, MacCoss MJ, Tsai LH, Jaffe JD. Litichevskiy L, et al. Cell Syst. 2018 Apr 25;6(4):424-443.e7. doi: 10.1016/j.cels.2018.03.012. Epub 2018 Apr 11. Cell Syst. 2018. PMID: 29655704 Free PMC article.
Prenatal diagnosis and molecular cytogenetic characterization of a chromosome 1q42.3-q44 deletion in a fetus associated with ventriculomegaly on prenatal ultrasound.
Chen CP, Ko TM, Wang LK, Chern SR, Wu PS, Chen SW, Wu FT, Chen YY, Chen WL, Wang W. Chen CP, et al. Among authors: ko tm. Taiwan J Obstet Gynecol. 2020 Jul;59(4):598-603. doi: 10.1016/j.tjog.2020.05.022. Taiwan J Obstet Gynecol. 2020. PMID: 32653137
Frequently abnormal serum gamma-glutamyl transferase activity is associated with future development of fatty liver: a retrospective cohort study.
Fujii H, Doi H, Ko T, Fukuma T, Kadono T, Asaeda K, Kobayashi R, Nakano T, Doi T, Nakatsugawa Y, Yamada S, Nishimura T, Tomatsuri N, Sato H, Okuyama Y, Kimura H, Kishimoto E, Nakabe N, Shima T. Fujii H, et al. Among authors: ko t. BMC Gastroenterol. 2020 Jul 10;20(1):217. doi: 10.1186/s12876-020-01369-x. BMC Gastroenterol. 2020. PMID: 32650722 Free PMC article.
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