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Glucose catabolism in the rabbit VX2 tumor model for liver cancer: characterization and targeting hexokinase.
Ko YH, Pedersen PL, Geschwind JF. Ko YH, et al. Cancer Lett. 2001 Nov 8;173(1):83-91. doi: 10.1016/s0304-3835(01)00667-x. Cancer Lett. 2001. PMID: 11578813
Mitochondrial bound type II hexokinase: a key player in the growth and survival of many cancers and an ideal prospect for therapeutic intervention.
Pedersen PL, Mathupala S, Rempel A, Geschwind JF, Ko YH. Pedersen PL, et al. Among authors: ko yh. Biochim Biophys Acta. 2002 Sep 10;1555(1-3):14-20. doi: 10.1016/s0005-2728(02)00248-7. Biochim Biophys Acta. 2002. PMID: 12206885
Mitochondrial F(0)F(1) ATP synthase. Subunit regions on the F1 motor shielded by F(0), Functional significance, and evidence for an involvement of the unique F(0) subunit F(6).
Ko YH, Hullihen J, Hong S, Pedersen PL. Ko YH, et al. J Biol Chem. 2000 Oct 20;275(42):32931-9. doi: 10.1074/jbc.M004453200. J Biol Chem. 2000. PMID: 10887193
Delta subunit of rat liver mitochondrial ATP synthase: molecular description and novel insights into the nature of its association with the F1-moiety.
Pan W, Ko YH, Pedersen PL. Pan W, et al. Among authors: ko yh. Biochemistry. 1998 May 12;37(19):6911-23. doi: 10.1021/bi9800698. Biochemistry. 1998. PMID: 9578578
Cystic fibrosis, lung infections, and a human tracheal antimicrobial peptide (hTAP).
Ko YH, Delannoy M, Pedersen PL. Ko YH, et al. FEBS Lett. 1997 Mar 24;405(2):200-8. doi: 10.1016/s0014-5793(97)00189-0. FEBS Lett. 1997. PMID: 9089291
Altered protein folding may be the molecular basis of most cases of cystic fibrosis.
Thomas PJ, Ko YH, Pedersen PL. Thomas PJ, et al. Among authors: ko yh. FEBS Lett. 1992 Nov 2;312(1):7-9. doi: 10.1016/0014-5793(92)81399-7. FEBS Lett. 1992. PMID: 1385213 Review.
ATP synthase motor components: proposal and animation of two dynamic models for stator function.
Blum DJ, Ko YH, Hong S, Rini DA, Pedersen PL. Blum DJ, et al. Among authors: ko yh. Biochem Biophys Res Commun. 2001 Oct 5;287(4):801-7. doi: 10.1006/bbrc.2001.5634. Biochem Biophys Res Commun. 2001. PMID: 11573932
Cystic fibrosis transmembrane conductance regulator: the NBF1+R (nucleotide-binding fold 1 and regulatory domain) segment acting alone catalyses a Co2+/Mn2+/Mg2+-ATPase activity markedly inhibited by both Cd2+ and the transition-state analogue orthovanadate.
Annereau JP, Ko YH, Pedersen PL. Annereau JP, et al. Among authors: ko yh. Biochem J. 2003 Apr 15;371(Pt 2):451-62. doi: 10.1042/BJ20021318. Biochem J. 2003. PMID: 12523935 Free PMC article.
Chemical mechanism of ATP synthase. Magnesium plays a pivotal role in formation of the transition state where ATP is synthesized from ADP and inorganic phosphate.
Ko YH, Hong S, Pedersen PL. Ko YH, et al. J Biol Chem. 1999 Oct 8;274(41):28853-6. doi: 10.1074/jbc.274.41.28853. J Biol Chem. 1999. PMID: 10506126
In an earlier report (Ko, Y. H., Bianchet, M. A., Amzel, L.M., and Pedersen, P. L. (1997) J. Biol. Chem. 272, 18875-18881), we provided evidence for transition state formation in the presence of Mg(2+), ADP, and orthovanadate (V(i)), a photoreactive phosphate analog with a …
In an earlier report (Ko, Y. H., Bianchet, M. A., Amzel, L.M., and Pedersen, P. L. (1997) J. Biol. Chem. 272, 18875-18881), we provid …
ATP synthases in the year 2000: evolving views about the structures of these remarkable enzyme complexes.
Pedersen PL, Ko YH, Hong S. Pedersen PL, et al. Among authors: ko yh. J Bioenerg Biomembr. 2000 Aug;32(4):325-32. doi: 10.1023/a:1005594800983. J Bioenerg Biomembr. 2000. PMID: 11768293
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