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Patient-derived organoids from endometrial disease capture clinical heterogeneity and are amenable to drug screening.
Boretto M, Maenhoudt N, Luo X, Hennes A, Boeckx B, Bui B, Heremans R, Perneel L, Kobayashi H, Van Zundert I, Brems H, Cox B, Ferrante M, Uji-I H, Koh KP, D'Hooghe T, Vanhie A, Vergote I, Meuleman C, Tomassetti C, Lambrechts D, Vriens J, Timmerman D, Vankelecom H. Boretto M, et al. Among authors: kobayashi h. Nat Cell Biol. 2019 Aug;21(8):1041-1051. doi: 10.1038/s41556-019-0360-z. Epub 2019 Aug 1. Nat Cell Biol. 2019. PMID: 31371824
Interleukin-6 is an activator of pituitary stem cells upon local damage, a competence quenched in the aging gland.
Vennekens A, Laporte E, Hermans F, Cox B, Modave E, Janiszewski A, Nys C, Kobayashi H, Malengier-Devlies B, Chappell J, Matthys P, Garcia MI, Pasque V, Lambrechts D, Vankelecom H. Vennekens A, et al. Among authors: kobayashi h. Proc Natl Acad Sci U S A. 2021 Jun 22;118(25):e2100052118. doi: 10.1073/pnas.2100052118. Proc Natl Acad Sci U S A. 2021. PMID: 34161279 Free PMC article.
Exploring stem cell biology in pituitary tumors and derived organoids.
Nys C, Lee YL, Roose H, Mertens F, De Pauw E, Kobayashi H, Sciot R, Bex M, Versyck G, De Vleeschouwer S, Van Loon J, Laporte E, Vankelecom H. Nys C, et al. Among authors: kobayashi h. Endocr Relat Cancer. 2022 Jun 17;29(7):427-450. doi: 10.1530/ERC-21-0374. Endocr Relat Cancer. 2022. PMID: 35521774
9,294 results