Koch L - Search Results

1

Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity.

Plum L, Ma X, Hampel B, Balthasar N, Coppari R, Münzberg H, Shanabrough M, Burdakov D, Rother E, Janoschek R, Alber J, Belgardt BF, Koch L, Seibler J, Schwenk F, Fekete C, Suzuki A, Mak TW, Krone W, Horvath TL, Ashcroft FM, Brüning JC. Plum L, et al. Among authors: koch l. J Clin Invest. 2006 Jul;116(7):1886-901. doi: 10.1172/JCI27123. Epub 2006 Jun 22. J Clin Invest. 2006. PMID: 16794735 Free PMC article.

2

gp130 signaling in proopiomelanocortin neurons mediates the acute anorectic response to centrally applied ciliary neurotrophic factor.

Janoschek R, Plum L, Koch L, Münzberg H, Diano S, Shanabrough M, Müller W, Horvath TL, Brüning JC. Janoschek R, et al. Among authors: koch l. Proc Natl Acad Sci U S A. 2006 Jul 11;103(28):10707-12. doi: 10.1073/pnas.0600425103. Epub 2006 Jul 3. Proc Natl Acad Sci U S A. 2006. PMID: 16818888 Free PMC article.

3

Central insulin action regulates peripheral glucose and fat metabolism in mice.

Koch L, Wunderlich FT, Seibler J, Könner AC, Hampel B, Irlenbusch S, Brabant G, Kahn CR, Schwenk F, Brüning JC. Koch L, et al. J Clin Invest. 2008 Jun;118(6):2132-47. doi: 10.1172/JCI31073. J Clin Invest. 2008. PMID: 18451994 Free PMC article.

4

The fat mass and obesity associated gene (Fto) regulates activity of the dopaminergic midbrain circuitry.

Hess ME, Hess S, Meyer KD, Verhagen LA, Koch L, Brönneke HS, Dietrich MO, Jordan SD, Saletore Y, Elemento O, Belgardt BF, Franz T, Horvath TL, Rüther U, Jaffrey SR, Kloppenburg P, Brüning JC. Hess ME, et al. Among authors: koch l. Nat Neurosci. 2013 Aug;16(8):1042-8. doi: 10.1038/nn.3449. Epub 2013 Jun 30. Nat Neurosci. 2013. PMID: 23817550

5

Autocrine IGF-1 action in adipocytes controls systemic IGF-1 concentrations and growth.

Klöting N, Koch L, Wunderlich T, Kern M, Ruschke K, Krone W, Brüning JC, Blüher M. Klöting N, et al. Among authors: koch l. Diabetes. 2008 Aug;57(8):2074-82. doi: 10.2337/db07-1538. Epub 2008 Apr 28. Diabetes. 2008. PMID: 18443199 Free PMC article.

6

Phosphoinositide-dependent kinase 1 provides negative feedback inhibition to Toll-like receptor-mediated NF-kappaB activation in macrophages.

Chaurasia B, Mauer J, Koch L, Goldau J, Kock AS, Brüning JC. Chaurasia B, et al. Among authors: koch l. Mol Cell Biol. 2010 Sep;30(17):4354-66. doi: 10.1128/MCB.00069-10. Epub 2010 Jun 28. Mol Cell Biol. 2010. PMID: 20584979 Free PMC article.

7

Divergent roles of growth factors in the GnRH regulation of puberty in mice.

Divall SA, Williams TR, Carver SE, Koch L, Brüning JC, Kahn CR, Wondisford F, Radovick S, Wolfe A. Divall SA, et al. Among authors: koch l. J Clin Invest. 2010 Aug;120(8):2900-9. doi: 10.1172/JCI41069. Epub 2010 Jul 12. J Clin Invest. 2010. PMID: 20628204 Free PMC article.

8

Inactivation of the Fto gene protects from obesity.

Fischer J, Koch L, Emmerling C, Vierkotten J, Peters T, Brüning JC, Rüther U. Fischer J, et al. Among authors: koch l. Nature. 2009 Apr 16;458(7240):894-8. doi: 10.1038/nature07848. Epub 2009 Feb 22. Nature. 2009. PMID: 19234441

9

Neuronal IGF-1 resistance reduces Abeta accumulation and protects against premature death in a model of Alzheimer's disease.

Freude S, Hettich MM, Schumann C, Stöhr O, Koch L, Köhler C, Udelhoven M, Leeser U, Müller M, Kubota N, Kadowaki T, Krone W, Schröder H, Brüning JC, Schubert M. Freude S, et al. Among authors: koch l. FASEB J. 2009 Oct;23(10):3315-24. doi: 10.1096/fj.09-132043. Epub 2009 Jun 1. FASEB J. 2009. PMID: 19487308

10

Epidermal insulin/IGF-1 signalling control interfollicular morphogenesis and proliferative potential through Rac activation.

Stachelscheid H, Ibrahim H, Koch L, Schmitz A, Tscharntke M, Wunderlich FT, Scott J, Michels C, Wickenhauser C, Haase I, Brüning JC, Niessen CM. Stachelscheid H, et al. Among authors: koch l. EMBO J. 2008 Aug 6;27(15):2091-101. doi: 10.1038/emboj.2008.141. Epub 2008 Jul 24. EMBO J. 2008. PMID: 18650937 Free PMC article.

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