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Terphenyl-Based Small-Molecule Inhibitors of Programmed Cell Death-1/Programmed Death-Ligand 1 Protein-Protein Interaction.
J Med Chem. 2021 Aug 12;64(15):11614-11636. doi: 10.1021/acs.jmedchem.1c00957. Epub 2021 Jul 27.
J Med Chem. 2021.
PMID: 34313116
Free PMC article.
PD-L1 Inhibitors: Different Classes, Activities, and Mechanisms of Action.
Surmiak E, Magiera-Mularz K, Musielak B, Muszak D, Kocik-Krol J, Kitel R, Plewka J, Holak TA, Skalniak L.
Surmiak E, et al. Among authors: kocik krol j.
Int J Mol Sci. 2021 Oct 30;22(21):11797. doi: 10.3390/ijms222111797.
Int J Mol Sci. 2021.
PMID: 34769226
Free PMC article.
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Biphenyl Ether Analogs Containing Pomalidomide as Small-Molecule Inhibitors of the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Interaction.
Shaabani S, Gadina L, Surmiak E, Wang Z, Zhang B, Butera R, Zarganes-Tzitzikas T, Rodriguez I, Kocik-Krol J, Magiera-Mularz K, Skalniak L, Dömling A, Holak TA.
Shaabani S, et al. Among authors: kocik krol j.
Molecules. 2022 May 27;27(11):3454. doi: 10.3390/molecules27113454.
Molecules. 2022.
PMID: 35684392
Free PMC article.
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Design, Synthesis, and Biological Evaluation of 2-Hydroxy-4-phenylthiophene-3-carbonitrile as PD-L1 Antagonist and Its Comparison to Available Small Molecular PD-L1 Inhibitors.
Ważyńska MA, Butera R, Requesens M, Plat A, Zarganes-Tzitzikas T, Neochoritis CG, Plewka J, Skalniak L, Kocik-Krol J, Musielak B, Magiera-Mularz K, Rodriguez I, Blok SN, de Bruyn M, Nijman HW, Elsinga PH, Holak TA, Dömling A.
Ważyńska MA, et al. Among authors: kocik krol j.
J Med Chem. 2023 Jul 27;66(14):9577-9591. doi: 10.1021/acs.jmedchem.3c00254. Epub 2023 Jul 14.
J Med Chem. 2023.
PMID: 37450644
Free PMC article.
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Structural and biological characterization of pAC65, a macrocyclic peptide that blocks PD-L1 with equivalent potency to the FDA-approved antibodies.
Rodriguez I, Kocik-Krol J, Skalniak L, Musielak B, Wisniewska A, Ciesiołkiewicz A, Berlicki Ł, Plewka J, Grudnik P, Stec M, Siedlar M, Holak TA, Magiera-Mularz K.
Rodriguez I, et al. Among authors: kocik krol j.
Mol Cancer. 2023 Sep 7;22(1):150. doi: 10.1186/s12943-023-01853-4.
Mol Cancer. 2023.
PMID: 37679783
Free PMC article.
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Solubilizer Tag Effect on PD-L1/Inhibitor Binding Properties for m-Terphenyl Derivatives.
Surmiak E, Ząber J, Plewka J, Wojtanowicz G, Kocik-Krol J, Kruc O, Muszak D, Rodríguez I, Musielak B, Viviano M, Castellano S, Skalniak L, Magiera-Mularz K, Holak TA, Kalinowska-Tłuścik J.
Surmiak E, et al. Among authors: kocik krol j.
ACS Med Chem Lett. 2023 Dec 14;15(1):36-44. doi: 10.1021/acsmedchemlett.3c00306. eCollection 2024 Jan 11.
ACS Med Chem Lett. 2023.
PMID: 38229762
Free PMC article.
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