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The BMP pathway either enhances or inhibits the Wnt pathway depending on the SMAD4 and p53 status in CRC.
Voorneveld PW, Kodach LL, Jacobs RJ, van Noesel CJ, Peppelenbosch MP, Korkmaz KS, Molendijk I, Dekker E, Morreau H, van Pelt GW, Tollenaar RA, Mesker W, Hawinkels LJ, Paauwe M, Verspaget HW, Geraets DT, Hommes DW, Offerhaus GJ, van den Brink GR, Ten Dijke P, Hardwick JC. Voorneveld PW, et al. Among authors: kodach ll. Br J Cancer. 2015 Jan 6;112(1):122-30. doi: 10.1038/bjc.2014.560. Epub 2014 Nov 13. Br J Cancer. 2015. PMID: 25393365 Free PMC article.
SMAD4 exerts a tumor-promoting role in hepatocellular carcinoma.
Hernanda PY, Chen K, Das AM, Sideras K, Wang W, Li J, Cao W, Bots SJ, Kodach LL, de Man RA, Ijzermans JN, Janssen HL, Stubbs AP, Sprengers D, Bruno MJ, Metselaar HJ, ten Hagen TL, Kwekkeboom J, Peppelenbosch MP, Pan Q. Hernanda PY, et al. Among authors: kodach ll. Oncogene. 2015 Sep 24;34(39):5055-68. doi: 10.1038/onc.2014.425. Epub 2014 Dec 22. Oncogene. 2015. PMID: 25531314
Cholesterol metabolism and colorectal cancers.
Jacobs RJ, Voorneveld PW, Kodach LL, Hardwick JC. Jacobs RJ, et al. Among authors: kodach ll. Curr Opin Pharmacol. 2012 Dec;12(6):690-5. doi: 10.1016/j.coph.2012.07.010. Epub 2012 Aug 8. Curr Opin Pharmacol. 2012. PMID: 22884562 Review.
Correction: Kinome-wide analysis of the effect of statins in colorectal cancer.
Ouahoud S, Jacobs RJ, Peppelenbosch MP, Fühler GM, Heijmans J, Diks S, Wildenberg ME, Hawinkels LJAC, Kodach LL, Voorneveld PW, Hardwick JCH. Ouahoud S, et al. Among authors: kodach ll. Br J Cancer. 2021 May 10. doi: 10.1038/s41416-021-01426-6. Online ahead of print. Br J Cancer. 2021. PMID: 33972748 No abstract available.
Kinome-wide analysis of the effect of statins in colorectal cancer.
Ouahoud S, Jacobs RJ, Peppelenbosch MP, Fühler GM, Heijmans J, Diks S, Wildenberg ME, Hawinkels LJAC, Kodach LL, Voorneveld PW, Hardwick JCH. Ouahoud S, et al. Among authors: kodach ll. Br J Cancer. 2021 Jun;124(12):1978-1987. doi: 10.1038/s41416-021-01318-9. Epub 2021 Mar 19. Br J Cancer. 2021. PMID: 33742146
High CD8+ tumour-infiltrating lymphocyte density associates with unfavourable prognosis in oesophageal adenocarcinoma following poor response to neoadjuvant chemoradiotherapy.
Koemans WJ, van Dieren JM, van den Berg JG, Meijer GA, Snaebjornsson P, Chalabi M, Lecot F, Riedl R, Krijgsman O, Hofland I, Broeks A, Voncken FEM, Peppelenbosch MP, Sosef MN, van Sandick JW, Kodach LL. Koemans WJ, et al. Among authors: kodach ll. Histopathology. 2021 Mar 4. doi: 10.1111/his.14361. Online ahead of print. Histopathology. 2021. PMID: 33660299
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