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A two-in-one antibody engineered from a humanized interleukin 4 antibody through mutation in heavy chain complementarity-determining regions.
Lee CV, Koenig P, Fuh G. Lee CV, et al. Among authors: koenig p. MAbs. 2014 May-Jun;6(3):622-7. doi: 10.4161/mabs.28483. Epub 2014 Mar 11. MAbs. 2014. PMID: 24618680 Free PMC article.
Tuning the specificity of a Two-in-One Fab against three angiogenic antigens by fully utilizing the information of deep mutational scanning.
Koenig P, Sanowar S, Lee CV, Fuh G. Koenig P, et al. MAbs. 2017 Aug/Sep;9(6):959-967. doi: 10.1080/19420862.2017.1337618. Epub 2017 Jun 6. MAbs. 2017. PMID: 28585908 Free PMC article.
Mutational landscape of antibody variable domains reveals a switch modulating the interdomain conformational dynamics and antigen binding.
Koenig P, Lee CV, Walters BT, Janakiraman V, Stinson J, Patapoff TW, Fuh G. Koenig P, et al. Proc Natl Acad Sci U S A. 2017 Jan 24;114(4):E486-E495. doi: 10.1073/pnas.1613231114. Epub 2017 Jan 5. Proc Natl Acad Sci U S A. 2017. PMID: 28057863 Free PMC article.
Deep Sequencing-guided Design of a High Affinity Dual Specificity Antibody to Target Two Angiogenic Factors in Neovascular Age-related Macular Degeneration.
Koenig P, Lee CV, Sanowar S, Wu P, Stinson J, Harris SF, Fuh G. Koenig P, et al. J Biol Chem. 2015 Sep 4;290(36):21773-86. doi: 10.1074/jbc.M115.662783. Epub 2015 Jun 18. J Biol Chem. 2015. PMID: 26088137 Free PMC article.
High affinity antigen recognition of the dual specific variants of herceptin is entropy-driven in spite of structural plasticity.
Bostrom J, Haber L, Koenig P, Kelley RF, Fuh G. Bostrom J, et al. Among authors: koenig p. PLoS One. 2011 Apr 22;6(4):e17887. doi: 10.1371/journal.pone.0017887. PLoS One. 2011. PMID: 21526167 Free PMC article.
Selection and screening using antibody phage display libraries.
Koenig P, Fuh G. Koenig P, et al. Methods Mol Biol. 2014;1131:133-49. doi: 10.1007/978-1-62703-992-5_9. Methods Mol Biol. 2014. PMID: 24515464
On the significance of Toc-GTPase homodimers.
Koenig P, Oreb M, Rippe K, Muhle-Goll C, Sinning I, Schleiff E, Tews I. Koenig P, et al. J Biol Chem. 2008 Aug 22;283(34):23104-12. doi: 10.1074/jbc.M710576200. Epub 2008 Jun 8. J Biol Chem. 2008. PMID: 18541539
Conserved properties of polypeptide transport-associated (POTRA) domains derived from cyanobacterial Omp85.
Koenig P, Mirus O, Haarmann R, Sommer MS, Sinning I, Schleiff E, Tews I. Koenig P, et al. J Biol Chem. 2010 Jun 4;285(23):18016-24. doi: 10.1074/jbc.M110.112649. Epub 2010 Mar 26. J Biol Chem. 2010. PMID: 20348103 Free PMC article.
Asymmetric electrostatic and hydrophobic-hydrophilic interaction forces between mica surfaces and silicone polymer thin films.
Donaldson SH Jr, Das S, Gebbie MA, Rapp M, Jones LC, Roiter Y, Koenig PH, Gizaw Y, Israelachvili JN. Donaldson SH Jr, et al. Among authors: koenig ph. ACS Nano. 2013 Nov 26;7(11):10094-104. doi: 10.1021/nn4050112. Epub 2013 Oct 23. ACS Nano. 2013. PMID: 24138532
The GTPase cycle of the chloroplast import receptors Toc33/Toc34: implications from monomeric and dimeric structures.
Koenig P, Oreb M, Höfle A, Kaltofen S, Rippe K, Sinning I, Schleiff E, Tews I. Koenig P, et al. Structure. 2008 Apr;16(4):585-96. doi: 10.1016/j.str.2008.01.008. Structure. 2008. PMID: 18400179
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