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Cyclosporin binding to a protein component of the renal Na(+)-D-glucose cotransporter.
Ziegler K, Frimmer M, Fritzsch G, Koepsell H. Ziegler K, et al. Among authors: koepsell h. J Biol Chem. 1990 Feb 25;265(6):3270-7. J Biol Chem. 1990. PMID: 2303450
The immunosuppressive and nephrotoxic agent cyclosporin binds to a renal polypeptide with an apparent molecular weight of 75,000 which has been identified as a component of the renal Na(+)-D-glucose cotransporter (Neeb, M., Kunz, U., and Koepsell, H. (1987) J. Biol. …
The immunosuppressive and nephrotoxic agent cyclosporin binds to a renal polypeptide with an apparent molecular weight of 75,000 which has b …
Monoclonal antibodies against the renal Na+-D-glucose cotransporter. Identification of antigenic polypeptides and demonstration of functional coupling of different Na+-cotransport systems.
Koepsell H, Korn K, Raszeja-Specht A, Bernotat-Danielowski S, Ollig D. Koepsell H, et al. J Biol Chem. 1988 Dec 5;263(34):18419-29. J Biol Chem. 1988. PMID: 2461369
In porcine renal brush-border membranes, the antibodies either bind to one or to three polypeptides which have been identified as components of the Na+-D-glucose cotransporter (Neeb, M., Kunz, U., and Koepsell, H., (1987) J. Biol. Chem. 262, 10718-10727). Their mole …
In porcine renal brush-border membranes, the antibodies either bind to one or to three polypeptides which have been identified as components …
Cloning of a membrane-associated protein which modifies activity and properties of the Na(+)-D-glucose cotransporter.
Veyhl M, Spangenberg J, Püschel B, Poppe R, Dekel C, Fritzsch G, Haase W, Koepsell H. Veyhl M, et al. Among authors: koepsell h. J Biol Chem. 1993 Nov 25;268(33):25041-53. J Biol Chem. 1993. PMID: 8227068
Thus with SGLT1 one apparent transport site (K0.5 about 100 microM) and one apparent phlorizin inhibition site (Ki about 5 microM) was observed whereas with SGLT1 plus RS1 two apparent transport sites (K0.5(1) about 20 microM, K0.5(2) about 1 mM) and two apparent phlorizin inhibi …
Thus with SGLT1 one apparent transport site (K0.5 about 100 microM) and one apparent phlorizin inhibition site (Ki about 5 microM) was obser …
Electrogenic properties and substrate specificity of the polyspecific rat cation transporter rOCT1.
Busch AE, Quester S, Ulzheimer JC, Waldegger S, Gorboulev V, Arndt P, Lang F, Koepsell H. Busch AE, et al. Among authors: koepsell h. J Biol Chem. 1996 Dec 20;271(51):32599-604. doi: 10.1074/jbc.271.51.32599. J Biol Chem. 1996. PMID: 8955087
The previously cloned rat cation transporter rOCT1 detected in renal proximal tubules and hepatocytes (Grundemann, D., Gorboulev, V., Gambaryan, S., Veyhl, M., and Koepsell, H. (1994) Nature 372, 549-552) was expressed in Xenopus oocytes, and transport properties we …
The previously cloned rat cation transporter rOCT1 detected in renal proximal tubules and hepatocytes (Grundemann, D., Gorboulev, V., Gambar …
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