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Page 1
Endotheliopathy in COVID-19-associated coagulopathy: evidence from a single-centre, cross-sectional study.
Goshua G, Pine AB, Meizlish ML, Chang CH, Zhang H, Bahel P, Baluha A, Bar N, Bona RD, Burns AJ, Dela Cruz CS, Dumont A, Halene S, Hwa J, Koff J, Menninger H, Neparidze N, Price C, Siner JM, Tormey C, Rinder HM, Chun HJ, Lee AI. Goshua G, et al. Among authors: koff j. Lancet Haematol. 2020 Aug;7(8):e575-e582. doi: 10.1016/S2352-3026(20)30216-7. Epub 2020 Jun 30. Lancet Haematol. 2020. PMID: 32619411 Free PMC article. Clinical Trial.
A neutrophil activation signature predicts critical illness and mortality in COVID-19.
Meizlish ML, Pine AB, Bishai JD, Goshua G, Nadelmann ER, Simonov M, Chang CH, Zhang H, Shallow M, Bahel P, Owusu K, Yamamoto Y, Arora T, Atri DS, Patel A, Gbyli R, Kwan J, Won CH, Dela Cruz C, Price C, Koff J, King BA, Rinder HM, Wilson FP, Hwa J, Halene S, Damsky W, van Dijk D, Lee AI, Chun HJ. Meizlish ML, et al. Among authors: koff j. Blood Adv. 2021 Mar 9;5(5):1164-1177. doi: 10.1182/bloodadvances.2020003568. Blood Adv. 2021. PMID: 33635335 Free PMC article.
A neutrophil activation signature predicts critical illness and mortality in COVID-19.
Meizlish ML, Pine AB, Bishai JD, Goshua G, Nadelmann ER, Simonov M, Chang CH, Zhang H, Shallow M, Bahel P, Owusu K, Yamamoto Y, Arora T, Atri DS, Patel A, Gbyli R, Kwan J, Won CH, Dela Cruz C, Price C, Koff J, King BA, Rinder HM, Wilson FP, Hwa J, Halene S, Damsky W, van Dijk D, Lee AI, Chun H. Meizlish ML, et al. Among authors: koff j. medRxiv [Preprint]. 2020 Sep 2:2020.09.01.20183897. doi: 10.1101/2020.09.01.20183897. medRxiv. 2020. PMID: 32908988 Free PMC article. Updated. Preprint.
A Clinic Blueprint for Post-Coronavirus Disease 2019 RECOVERY: Learning From the Past, Looking to the Future.
Lutchmansingh DD, Knauert MP, Antin-Ozerkis DE, Chupp G, Cohn L, Dela Cruz CS, Ferrante LE, Herzog EL, Koff J, Rochester CL, Ryu C, Singh I, Tickoo M, Winks V, Gulati M, Possick JD. Lutchmansingh DD, et al. Among authors: koff j. Chest. 2021 Mar;159(3):949-958. doi: 10.1016/j.chest.2020.10.067. Epub 2020 Nov 4. Chest. 2021. PMID: 33159907 Free PMC article. Review.
Respiratory syncytial virus activates epidermal growth factor receptor to suppress interferon regulatory factor 1-dependent interferon-lambda and antiviral defense in airway epithelium.
Kalinowski A, Galen BT, Ueki IF, Sun Y, Mulenos A, Osafo-Addo A, Clark B, Joerns J, Liu W, Nadel JA, Dela Cruz CS, Koff JL. Kalinowski A, et al. Among authors: koff jl. Mucosal Immunol. 2018 May;11(3):958-967. doi: 10.1038/mi.2017.120. Epub 2018 Feb 7. Mucosal Immunol. 2018. PMID: 29411775 Free PMC article.
Epidermal Growth Factor Receptor Inhibition Is Protective in Hyperoxia-Induced Lung Injury.
Harris ZM, Sun Y, Joerns J, Clark B, Hu B, Korde A, Sharma L, Shin HJ, Manning EP, Placek L, Unutmaz D, Stanley G, Chun H, Sauler M, Rajagopalan G, Zhang X, Kang MJ, Koff JL. Harris ZM, et al. Among authors: koff jl. Oxid Med Cell Longev. 2022 Sep 20;2022:9518592. doi: 10.1155/2022/9518592. eCollection 2022. Oxid Med Cell Longev. 2022. PMID: 36193076 Free PMC article.
"Small" Intestinal Immunopathology Plays a "Big" Role in Lethal Cytokine Release Syndrome, and Its Modulation by Interferon-γ, IL-17A, and a Janus Kinase Inhibitor.
Kale SD, Mehrkens BN, Stegman MM, Kastelberg B, Carnes H, McNeill RJ, Rizzo A, Karyala SV, Coutermarsh-Ott S, Fretz JA, Sun Y, Koff JL, Rajagopalan G. Kale SD, et al. Among authors: koff jl. Front Immunol. 2020 Jun 26;11:1311. doi: 10.3389/fimmu.2020.01311. eCollection 2020. Front Immunol. 2020. PMID: 32676080 Free PMC article.
I-SPY COVID adaptive platform trial for COVID-19 acute respiratory failure: rationale, design and operations.
Files DC, Matthay MA, Calfee CS, Aggarwal NR, Asare AL, Beitler JR, Berger PA, Burnham EL, Cimino G, Coleman MH, Crippa A, Discacciati A, Gandotra S, Gibbs KW, Henderson PT, Ittner CAG, Jauregui A, Khan KT, Koff JL, Lang J, LaRose M, Levitt J, Lu R, McKeehan JD, Meyer NJ, Russell DW, Thomas KW, Eklund M, Esserman LJ, Liu KD; ISPY COVID Adaptive Platform Trial Network; undefined. Files DC, et al. Among authors: koff jl. BMJ Open. 2022 Jun 6;12(6):e060664. doi: 10.1136/bmjopen-2021-060664. BMJ Open. 2022. PMID: 35667714 Free PMC article. Clinical Trial.
128 results