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Control of vascular morphogenesis and homeostasis through the angiopoietin-Tie system.
Augustin HG, Koh GY, Thurston G, Alitalo K. Augustin HG, et al. Nat Rev Mol Cell Biol. 2009 Mar;10(3):165-77. doi: 10.1038/nrm2639. Nat Rev Mol Cell Biol. 2009. PMID: 19234476 Review.
Vegfc is required for vascular development and endoderm morphogenesis in zebrafish.
Ober EA, Olofsson B, Mäkinen T, Jin SW, Shoji W, Koh GY, Alitalo K, Stainier DY. Ober EA, et al. EMBO Rep. 2004 Jan;5(1):78-84. doi: 10.1038/sj.embor.7400047. EMBO Rep. 2004. PMID: 14710191 Free PMC article.
Biological characterization of angiopoietin-3 and angiopoietin-4.
Lee HJ, Cho CH, Hwang SJ, Choi HH, Kim KT, Ahn SY, Kim JH, Oh JL, Lee GM, Koh GY. Lee HJ, et al. FASEB J. 2004 Aug;18(11):1200-8. doi: 10.1096/fj.03-1466com. FASEB J. 2004. PMID: 15284220
Angiopoietin-1 promotes LYVE-1-positive lymphatic vessel formation.
Morisada T, Oike Y, Yamada Y, Urano T, Akao M, Kubota Y, Maekawa H, Kimura Y, Ohmura M, Miyamoto T, Nozawa S, Koh GY, Alitalo K, Suda T. Morisada T, et al. Blood. 2005 Jun 15;105(12):4649-56. doi: 10.1182/blood-2004-08-3382. Epub 2005 Feb 10. Blood. 2005. PMID: 15705793
Multiple angiopoietin recombinant proteins activate the Tie1 receptor tyrosine kinase and promote its interaction with Tie2.
Saharinen P, Kerkelä K, Ekman N, Marron M, Brindle N, Lee GM, Augustin H, Koh GY, Alitalo K. Saharinen P, et al. J Cell Biol. 2005 Apr 25;169(2):239-43. doi: 10.1083/jcb.200411105. J Cell Biol. 2005. PMID: 15851516 Free PMC article.
Cooperative interaction of Angiopoietin-like proteins 1 and 2 in zebrafish vascular development.
Kubota Y, Oike Y, Satoh S, Tabata Y, Niikura Y, Morisada T, Akao M, Urano T, Ito Y, Miyamoto T, Nagai N, Koh GY, Watanabe S, Suda T. Kubota Y, et al. Proc Natl Acad Sci U S A. 2005 Sep 20;102(38):13502-7. doi: 10.1073/pnas.0501902102. Epub 2005 Sep 8. Proc Natl Acad Sci U S A. 2005. PMID: 16174743 Free PMC article.
In vivo actions of angiopoietins on quiescent and remodeling blood and lymphatic vessels in mouse airways and skin.
Kim KE, Cho CH, Kim HZ, Baluk P, McDonald DM, Koh GY. Kim KE, et al. Arterioscler Thromb Vasc Biol. 2007 Mar;27(3):564-70. doi: 10.1161/ Epub 2006 Dec 28. Arterioscler Thromb Vasc Biol. 2007. PMID: 17194894
Profound but dysfunctional lymphangiogenesis via vascular endothelial growth factor ligands from CD11b+ macrophages in advanced ovarian cancer.
Jeon BH, Jang C, Han J, Kataru RP, Piao L, Jung K, Cha HJ, Schwendener RA, Jang KY, Kim KS, Alitalo K, Koh GY. Jeon BH, et al. Cancer Res. 2008 Feb 15;68(4):1100-9. doi: 10.1158/0008-5472.CAN-07-2572. Cancer Res. 2008. PMID: 18281485
Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell-cell and cell-matrix contacts.
Saharinen P, Eklund L, Miettinen J, Wirkkala R, Anisimov A, Winderlich M, Nottebaum A, Vestweber D, Deutsch U, Koh GY, Olsen BR, Alitalo K. Saharinen P, et al. Nat Cell Biol. 2008 May;10(5):527-37. doi: 10.1038/ncb1715. Epub 2008 Apr 20. Nat Cell Biol. 2008. PMID: 18425119
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